›› 2013, Vol. 40 ›› Issue (10): 96-100.

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Study on the Compound Probiotics Instead of Opening Antibiotics in Broilers

XIE Quan-xi, ZHANG Jian-mei, GU Wei   

  1. Shandong Baolai-Leelai Bioengineering Co., Ltd., Tai'an 271000, China
  • Received:2013-03-25 Online:2013-10-20 Published:2013-12-19

Abstract: This experiment was conducted to investigate the effect of compound probiotics and opening antibiotics on the immune function,intestinal microflora and serum biochemical index of broilers.180 one-day-old female broilers with similar body weight were randomly divided into 3 groups with 3 replicates in each group and 20 chickens per replicate. The chickens in control group (group Ⅰ)were only fed with a basal diet,group Ⅱ was the compound probiotics group,supplemented with 2.0‰ compound probiotics, group Ⅲ was the antibiotics group by adding monensin (90 g/t),colistin (30 g/t) and arsanilic acid (100 g/t). The experiment lasted for 14 days. The results showed as follows: ①At the age of 14 days,the spleen index and the bursa of Fabricius index in group Ⅱ were all significantly higher than those in control group and group Ⅲ(P<0.05). ②At the age of 7 days,the number of cecal E.coli in group Ⅱ was significantly lower than that in control group(P<0.05). At the age of 14 days, the number of intestinal lactic acid bacteria in group Ⅱ was significantly higher than that in group Ⅲ(P<0.05). ③At the age of 14 days, the content of interleukin 2 in serum in group Ⅲ was significantly lower than those in group Ⅱ and control group(P<0.05), the content of glutamic-pyruvic transaminase was significantly higher than that in group Ⅱ(P<0.05);and at the same age,the urea nitrogen content in group Ⅱ was significantly lower than that in group Ⅲ(P<0.05). In conclusion,the supplementation of 2.0‰ compound probiotics could partially or completely replace opening antibiotics in broilers production.

Key words: compound probiotics; opening antibiotics; immune function; intestinal microflora; serum biochemical index

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