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Roles of Lactobacillus in Regulating Intestinal Barrier Functions

ZHU Cui1,2, SHI Zi-biao1,3, JIANG Zong-yong1, WANG Li1   

  1. 1. Guangdong Public Laboratory of Animal Breeding and Nutrition, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, P.R.China, State Key Laboratory of Livestock and Poultry Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640,China;
    2. College of Animal Science, South China Agricultural University, Guangzhou 510642,China;
    3. School of Life Sciences, Sun Yat-Sen University, Guangzhou 510006,China
  • Received:2012-02-07 Online:2012-09-20 Published:2012-09-18

Abstract: Lactobacilli is not only the normal commensal bacteria in the intestine of animals, but also makes up an important portion of probiotic. Intestinal barriers mainly include the immune barrier composed with intestinal mucosal immunity system, intestinal mucosal barrier composed with intestinal mucin layer and epithelial cell layer, as well as the biological barrier composed with gut microflora. This review mainly summarizes the regulative effects of Lactobacillus on intestinal barrier functions.

Key words: Lactobacillus; intestinal barrier function; permeability; tight junction

CLC Number: