单克隆抗体研究进展

Abstract

Abstract: Hybridization techniques have made mouse monoclonal antibody widely use in diagnosis and research of human disease, and established the first milestone of therapeutic antibody. With the biology development and antibody genetic structure clarification, people can humanize mouse antibody with DNA recombination and antibody library which developed antibody techniques from chimeric and reshaped to human antibody. Both humanized monoclonal antibody and its derivative overcome the clinical shortage of mouse antibody from different angles, also bring a new dawn to made antibody.

Key words: monoclonal antibody; mouse monoclonal antibody; human monoclonal antibody

CLC Number:

S859.79⁺7

LIU Ping;CHEN Miao-miao;LIU Xue-rong;MU Ke-bin;HUANG Yin-jun. Research Progress in Monoclonal Antibodies[J]. , 2012, 39(1): 67-70.

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Research Progress in Monoclonal Antibodies

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