›› 2011, Vol. 38 ›› Issue (7): 179-182.

• 疾病防治 • Previous Articles     Next Articles

Biological Characteristics and Pathogenicity of Two Haemophilus parasuis Strains Collected from South China

LI Ang, XU Cheng-gang, ZHANG Jian-min, GUO Li-li, ZHANG Bin, HE Yan-bing, ZHANG Ling-yun, REN Tao   

  1. Key Laboratory of Animal Diseases Control and Prevention of the Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
  • Received:2010-12-27 Revised:1900-01-01 Online:2011-07-20 Published:2011-07-20

Abstract: Two strains of Haemophilus parasuiswere studied on the characterization of colony culture, biological characteristics, serotype identification, resistance to drug, antigenicity and pathogenicity. The serological identification proved that one is 4 antigen type, and the other is 5 antigen type. The results showed that the two strains of Haemophilus parasuis multiplied rapidly and could reach 109 CFU in 10 h. Their LD50 are 1.52×109 CFU and 9.3×108 CFU. These two isolated strains had drug resistance to Fluoroquinolone antimicrobials and Sulfamethoxazole and Trimethoprium (SXT). They all have high immunogenicity. These results indicate that these two strains of Haemophilus parasuiscould be the candidate vaccine strains.

Key words: Haemophilus parasuis; biological characteristics; growth curve; LD50

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