›› 2011, Vol. 38 ›› Issue (7): 148-150.

• 遗传繁育 • Previous Articles     Next Articles

Effect of Omethoate on the Testis Succinic Dehydrogenase (SDH) and the Quality of Sperm in Male Mice

XU Guang-cui1, GAO Qi-yu2, HAN Guang-liang1, WANG Er-man1   

  1. 1. Toxicology Teaching and Research Section of the Department of Public Health, Xinxiang Medical University, Xinxiang 453003,China;2. Applied Biology Section of the Department of Life Science and Technology, Xinxiang Medical University, Xinxiang 453003,China
  • Received:2010-12-27 Revised:1900-01-01 Online:2011-07-20 Published:2011-07-20

Abstract: To explore the adverse effect of omethoate on activity of the testicle succinic dehydrogenase (SDH) and the quality of sperm in mice. 40 male Kunming mice were distributed randomly into 4 groups including the control group, low dose omethote (1.0 mg/kg), middle dose omethote(2.0 mg/kg) and high dose omethote (4.0 mg/kg). The experiment groups were primed through mouth with omethoate and the control group with 0.9% saline for 14 days. As the omethoate doses was increased, the activity of succinic dehydrogenase (SDH), the number of sperm and the rate of living sperm were decreased significantly compared with the control group(P＜0.05).The testis weight and epididymal viscera of mice were not statistically significant compared with the control group (P＞0.05). The omethoate was toxic to the reproductive system in the mice and could damage the density of sperm and the rate of living sperm, inhibit the activity of SDH.

Key words: reproductive toxicity; omethoate; SDH; the quality of sperm

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