›› 2016, Vol. 43 ›› Issue (3): 714-719.doi: 10.16431/j.cnki.1671-7236.2016.03.023

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Research Progress on Reproductive Toxicology

ZHAO Xiao-le, KONG Xiao-jun, LI Shi-hong, QIN Zhe, LIU Xi-wang, YANG Ya-jun, LI Jian-yong   

  1. Key Laboratory of New Animal Drug Project of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Science, CAAS, Lanzhou 730050, China
  • Received:2015-09-08 Online:2016-03-20 Published:2016-03-30

Abstract: With the deepening of modern biological science,obstetrics,pharmacology and toxicology intersect penetration with each other,thus gradually make the development of reproductive toxicology.Reproductive toxicology include two parts:Reproductive toxicology and developmental toxicology,it is a method focused on exploring whether there are influences of environmental and drugs factors on parental reproductive functions and the development of offspring.In this paper,the injury effects of test drugs on the reproductive cytogenesis,fertilization of egg cell,embryogenesis,pregnancy,childbirth,breast-feeding and development of newborn pups were summarized.

Key words: reproductive toxicity; developmental toxicity; new technology

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