Abstract: The immunohistochemical techniques were used in this experiment to discuss the effect of the corn protein polypeptide on fat fatty synthase (FAS) expression location in different tissues of geese. 240 one-day-old Changtu huoyan geese were randomly divided into 4 groups, each group set six repeats, each repeat with 10 geese. Among them, one control group was fed basal diet, the other three doses groups, per kilogram of basal diets supplemented with corn protein polypeptide 100, 300 and 500 mg, respectively. Then in 30-day-old and 60-day-old, the liver tissue and subcutaneous adipose of geese were collected to be applied in analyzing the expression and distribution of FAS by immunohistochemical method. The results indicated that in liver tissue and adipose tissue of geese, the FAS expressing was mainly distributed in the liver endothelial cell cytoplasm and nucleus and adipocyte membrane. With the increase of age, the content of FAS in liver and fat tissue of geese increased.Add corn protein polypeptide could promote the FAS expressing in livers of geese and restrain expressing in adipose tissue. Compared 60-day-old with 30-day-old, the FAS expression of livers in high, medium and low dose group, increased 47.75%、36.21% and 158.74%, respectively, but 11.00% in control group. Meantime corn protein polypeptide could restrain the FAS expression of the adipose tissue, decrease 22.34%, 46.43% and 49.17%, respectively. The results showed that the corn protein polypeptide showed a dual effect, low doses corn protein polypeptide （100 mg/kg diet） added for longer time in the diet of geese could effectively promote the FAS expressing in livers, reduce the FAS expressing in adipose tissue, so as to facilitate the regulation of the body lipid metabolism, improve the quality of carcasses.

Key words: corn protein polypeptide; immunohistochemical method; fatty acid synthetase; geese