Abstract: Nucleic acid vaccine in recent years is the concern of a new vaccine. Nucleic acid vaccines with its unique can induce organic produce a comprehensive immune response of the different type of pathogens overlapping defense and security, reliability and production facilities and other advantages is known as “vaccine 3rd revolution”. Nucleic acid vaccines were built by the code of protective immune response of pathogens antigen gene segments of the carrier and the vaccines including DNA vaccine and RNA vaccine research more than DNA vaccines. DNA vaccine is contained in the code antigen gene expression really nuclear DNA tablets of the body directly vaccination, may be somatic cell intake, and reproduced, expressed their corresponding translation, the antigen, and then through different means of stimulating organisms in such antigens of the answer. This gave a briefing on the animal nucleic acid vaccine characteristics, immunization, immunization factors as well as in the livestock and poultry communicable diseases in the application of the analysis of nucleic acid vaccine development prospects, thus the nucleic acid vaccines for the development of new ideas and new ways.

Key words: nucleic acid vaccine; status; prospects