›› 2009, Vol. 36 ›› Issue (11): 41-43.

• 生理生化 • Previous Articles     Next Articles

Study Progress in Bactericidal/Permeability Increasing Protein

XIAO Jing1, LI Xiao-li1,2, TONG Liang1, LI Yan-bing1, GUI Yi1, LI Jin-tao1, ZHANG Yi-fang1   

  1. (1.Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China;2.Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Jingzhou 434000, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-11-20 Published:2009-11-20
  • Contact: ZHANG Yi-fang

Abstract: The bactericidal/ permeability increasing protein (BPI), a cationic antibacterial and endotoxin-neutralizing activity protein located in neutrophilic granulocytes has a good prospect in clinical treatment of Gram-negative infections. The molecule structure, biological function, functional mechanisms and clinical research of BPI are summarized in this review.

Key words: bactericidal/permeability increasing protein; Gram negative bacteria; endotoxin

CLC Number: