›› 2018, Vol. 45 ›› Issue (12): 3513-3523.doi: 10.16431/j.cnki.1671-7236.2018.12.025

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Research Progress on the Follicle Stimulating Hormone Receptor Gene in Goats

JI Aiguo1, WANG Qingxiang2, SHEN Chao2   

  1. 1. Jincheng Institute of Technology, Jincheng 048026, China;
    2. Jincheng City Bureau of Animal Husbandry and Veterinary Medicine, Jincheng 048000, China
  • Received:2018-05-08 Online:2018-12-20 Published:2018-12-21

Abstract:

Follicle-stimulating hormone receptor (FSHR) gene,as a major gene affecting animal fertility,had been extensively and continuously studied in different species.The authors summarized and analyzed the structure of the goat FSHR gene and the corresponding protein's structure,action mechanism,expression scope and regularity,as well as the genetic effect of single nucleotide polymorphisms of the gene,and found that the research on the biological information and gene effects of goat FSHR gene had been carried out in depth,and the recent studies in signal transduction confirmed that FSHR gene was the key factor in the process of formation and development of ovarian follicles.Correlation analysis with reproductive performance of different populations suggested that some single nucleotide mutation sites of FSHR gene could be used as marker-assisted selection,but the mutation effects in different goat populations need to be further verified.

Key words: goat; FSHR gene; expression; genetic effect

CLC Number: