›› 2018, Vol. 45 ›› Issue (12): 3505-3512.doi: 10.16431/j.cnki.1671-7236.2018.12.024

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Application Status Analysis of Molecular Marker in Sheep Breeding

GUO Yingwei, SUN Kexin, TIAN Chen, CAO Rui, ZHAO Haidong, WANG Shuhui, SUN Xiuzhu   

  1. College of Animal Science and Technology, Northwest A & F University, Yangling 712100, China
  • Received:2018-03-05 Online:2018-12-20 Published:2018-12-21

Abstract:

Molecular markers are genetic markers based on nucleotide sequence variation in individuals,and they are direct responses to genetic diversity at the DNA level.Molecular marker technology is an efficient and accurate technical method for polymorphism analysis at the DNA level,it has been widely used in sheep breeding.Molecular marker technology can not only locate gene in sheep,but also analyze the genetic structure of sheep population.Additionally,molecular marker technology plays an important role in sheep breeding through marker-assisted breeding.This article briefly introduced the basic principles,advantages and disadvantages of molecular marker technology based on Southern hybridization,PCR,simple sequence repeat (SSR),and single nucleotide polymorphism (SNP).The application of these molecular markers in marker-assisted selection (MAS) among sheep's traits such as body size,slaughter,and reproduction reveals the importance of molecular marker technology for the selection and assortative mating of sheep and improving its economic value in actual production.Finally,the future application of molecular marker technology is prospected based on the application of molecular marker technology in sheep breeding.

Key words: molecular markers; marker-assisted selection (MAS); sheep breeding

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