›› 2017, Vol. 44 ›› Issue (11): 3229-3235.doi: 10.16431/j.cnki.1671-7236.2017.11.017

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Effects of Prostaglandin, N-methyl-D-aspartate and Letrozole on Ewes Plasma Levels of Reproductive Hormones were Evaluated on the Basis of Medroxyprogesterone Acetate Supplementation

ZHAO Guo-dong, WANG Gen, XIE Jing-long, YANG Jian-tao, TANG Xue-mei, ZHANG Juan-li, YANG Kai-lun   

  1. Xinjiang Key Laboratory of Meat & Milk Production Herbivore Nutrition, Xinjiang Agricultural University, Urumqi 830052, China
  • Received:2017-04-01 Online:2017-11-20 Published:2017-11-21

Abstract:

This study was aimed to investigate the effects of the different compatibility of medroxyprogesterone acetate (MPA) with prostaglandin(PG), N-methyl-D-aspartate (NMDA) and letrozole (LE) on plasma related hormones levels of reproductive ewes. Thirty-nine and 3-year-old multiparity Suffolk ewes with average weight (75.51+11.55)kg were selected,and assigned into 3 groups,test group Ⅰ:Basis diet+34 mg/d MPA+1 mL/ewe PG, test group Ⅱ:Basis diet+34 mg/d MPA+600 mg/d NMDA, test group Ⅲ:Basis diet+34 mg/d MPA+ 14 mg/d LE, respectively, the trial period lasted for 18 days. The results showed as follows:On the basis of supplemental feeding MPA with PG treated,the levels of FSH in plasma of ewes were extremely significantly increased (P<0.01); Treated with NMDA, the levels of E2, MLT,FSH and LH in plasma of ewes were extremely significantly increased (P<0.01), respectively;Treated with LE, the levels of MLT,LH and T in plasma of ewes were extremely significantly increased (P<0.01), respectively. This study suggested that MPA+NMDA and MPA+LE could be used as medicines for regulate and control oestrus of ewes, and the effect of MPA+NMDA was the best.

Key words: supplement; medroxyprogesterone acetate (MPA); prostaglandin (PG); N-methyl-D-aspartic acid (NMDA); letrozole (LE); ewes

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