光周期对于绒山羊毛囊干细胞激活的影响

doi:10.16431/j.cnki.1671-7236.2017.04.008

Abstract

Abstract:

In order to extend the anagen of cashmere goat hair follicles and increase the production of cashmere,this study was performed with artificially shorten the daylight time among Arbas White cashmere goats. Skin tissue sections from cashmere goats were collected to compare the morphologic changes between artificial daylight and natural daylight,and immunohistochemical method was used to study the hair follicle cell proliferation and important protein expression in related signaling pathways. The results showed that strong cell proliferation occurred in cashmere goat hair follicle cells during artificial daylight,plenty of cytokeratin 15 (K15) positive signals were distributed in the outer root sheath,β-catenin protein was actively expressed in hair matrix and root sheath, indicating that the hair follicles were in the anagen growth phase;Meanwhile,cashmere goat hair follicles under natural daylight were in telogen with weak signals. Above all prove that short photoperiod played an important role in promoting hair follicle growth,the artificial short photoperiod could change hair follicle growth cycle and make hair follicles earlier enter to the anagen growth phase,causing a variety of typical gene expressions during hair follicle growth.

Key words: cashmere goat; short photoperiod; cell proliferation; stem cells; growth regulation

CLC Number:

S826.9⁺1

LIU Bin, GUO Jun, Wudubala, MA Yue-jun, XIN Lei-yong, ZHAO Cun-fa, LI Yu-rong, YIN Jun. Effects of Photoperiod on Stem Cells Activation in Cashmere Goat Hair Follicles[J]. , 2017, 44(4): 994-1000.

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Effects of Photoperiod on Stem Cells Activation in Cashmere Goat Hair Follicles

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