体外精子发生培养方法研究进展

doi:10.16431/j.cnki.1671-7236.2015.11.033

Abstract

Abstract: The generation of functional sperm in vitro has been a goal for almost a century.Fortunately,researchers reported the successful in vitro production of functional sperm,thereby potentially opening up a new era of reproductive biology.In vitro cultural methods for spermatogenesis include tissue cultural method and cells cultural method.Take together transplanting isolated cells into testicular tissue for tissue culture.Here,we summarize the history of research directed toward reproducing steps of spermatogenesis in vitro,suggest ways that can be applied toward clinical applications and address fundamental questions about the underlying mechanism of spermatogenesis.

Key words: in vitro spermatogenesis; organ culture; germ cells; stem cells

CLC Number:

Q492

JI Meng, LI Xiang-chen, LI Lu, GUAN Wei-jun, MA Yue-hui. Advance of Cultural Methods for in vitro Spermatogenesis[J]. , 2015, 42(11): 3050-3055.

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