补饲醋酸甲羟孕酮基础上分别进行前列腺素、N-甲基-D-天冬氨酸和来曲唑处理对母羊血浆繁殖激素水平的影响

doi:10.16431/j.cnki.1671-7236.2017.11.017

摘要/Abstract

摘要：

试验旨在研究醋酸甲羟孕酮（medroxyprogesterone acetate，MPA）与前列腺素（prostaglandin，PG）、N-甲基-D-天冬氨酸（N-methyl-D-aspartate，NMDA）和来曲唑（letrozole，LE）的不同配伍对母羊血浆繁殖相关激素水平的影响。选取3岁经产萨福克母羊39只，平均体重（75.51±11.55） kg，随机均分为3组，试验Ⅰ组饲喂基础日粮+34 mg/（d·只） MPA+1 mL/只PG，试验Ⅱ组饲喂基础日粮+34 mg/（d·只） MPA+600 mg/（d·只） NMDA，试验Ⅲ组饲喂基础日粮+34 mg/（d·只） MPA+14 mg/（d·只） LE，试验期18 d。结果发现，补饲MPA基础上进行PG处理，母羊血浆中FSH水平呈极显著升高（P<0.01）；补饲MPA基础上进行NMDA处理，母羊血浆中E2、MLT、FSH和LH水平均呈极显著升高（P<0.01）；补饲MPA基础上进行LE处理，母羊血浆中MLT、LH和T水平均呈极显著升高（P<0.01）。综合比较各生殖激素之间的关系及变化规律，在本试验条件下，建议MPA与NMDA和LE分别结合使用，可作为调控母羊繁殖性能的药品；且通过比较激素水平得出，MPA与NMDA组合效果最佳。

关键词: 补饲; 醋酸甲羟孕酮; 前列腺素; N-甲基-D-天冬氨酸; 来曲唑; 母羊

Abstract:

This study was aimed to investigate the effects of the different compatibility of medroxyprogesterone acetate (MPA) with prostaglandin(PG), N-methyl-D-aspartate (NMDA) and letrozole (LE) on plasma related hormones levels of reproductive ewes. Thirty-nine and 3-year-old multiparity Suffolk ewes with average weight (75.51+11.55)kg were selected,and assigned into 3 groups,test group Ⅰ:Basis diet+34 mg/d MPA+1 mL/ewe PG, test group Ⅱ:Basis diet+34 mg/d MPA+600 mg/d NMDA, test group Ⅲ:Basis diet+34 mg/d MPA+ 14 mg/d LE, respectively, the trial period lasted for 18 days. The results showed as follows:On the basis of supplemental feeding MPA with PG treated,the levels of FSH in plasma of ewes were extremely significantly increased (P<0.01); Treated with NMDA, the levels of E₂, MLT,FSH and LH in plasma of ewes were extremely significantly increased (P<0.01), respectively;Treated with LE, the levels of MLT,LH and T in plasma of ewes were extremely significantly increased (P<0.01), respectively. This study suggested that MPA+NMDA and MPA+LE could be used as medicines for regulate and control oestrus of ewes, and the effect of MPA+NMDA was the best.

Key words: supplement; medroxyprogesterone acetate (MPA); prostaglandin (PG); N-methyl-D-aspartic acid (NMDA); letrozole (LE); ewes

中图分类号:

S814

赵国栋, 王根, 谢景龙, 杨健涛, 唐雪梅, 张娟丽, 杨开伦. 补饲醋酸甲羟孕酮基础上分别进行前列腺素、N-甲基-D-天冬氨酸和来曲唑处理对母羊血浆繁殖激素水平的影响[J]. 《中国畜牧兽医》, 2017, 44(11): 3229-3235.

ZHAO Guo-dong, WANG Gen, XIE Jing-long, YANG Jian-tao, TANG Xue-mei, ZHANG Juan-li, YANG Kai-lun. Effects of Prostaglandin, N-methyl-D-aspartate and Letrozole on Ewes Plasma Levels of Reproductive Hormones were Evaluated on the Basis of Medroxyprogesterone Acetate Supplementation[J]. , 2017, 44(11): 3229-3235.

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