[1] SI G, NIU J, ZHOU X, et al.Use of dual priming oligonucleotide system-based multiplex RT-PCR assay to detect five diarrhea viruses in pig herds in South China[J].AMB Express, 2021, 11(1):99. [2] ADHIKARI R B, ADHIKARI D M, THAPA S, et al.Gastrointestinal parasites of indigenous pigs (Sus domesticus) in South-Central Nepal[J].Veterinary Medicine and Science, 2021, 7(5):1820-1830. [3] 卢亚艺, 谢青, 唐棣, 等.菌痢消颗粒质量标准的研究[J].中国兽药杂志, 2009, 43(6):35-37. LU Y Y, XIE Q, TANG D, et al.Study on quality standard of Junlixiao granules[J].Chinese Journal of Veterinary Drug, 2009, 43(6):35-37.(in Chinese) [4] NOGALES C, MAMDOUH Z M, LIST M, et al.Network pharmacology:Curing causal mechanisms instead of treating symptoms[J].Trends in Pharmacological Sciences, 2022, 43(2):136-150. [5] RU J, LI P, WANG J, et al.TCMSP:A database of systems pharmacology for drug discovery from herbal medicines[J].Journal of Cheminformatics, 2014, 6:13. [6] XU H Y, ZHANG Y Q, LIU Z M, et al.ETCM:An encyclopaedia of traditional Chinese medicine[J].Nucleic Acids Research, 2019, 47(D1):D976-D982. [7] 崔恩慧, 赵善廷.基于网络药理学探究黄芩汤治疗猪腹泻的作用机制[J].动物医学进展, 2021, 42(11):111-116. CUI E H, ZHAO S T.Mechanism of huangqin decoction in treating swine diarrhea based on network pharmacology[J].Progress in Veterinary Medicine, 2021, 42(11):111-116.(in Chinese) [8] 江宇宁, 张淑洁, 何云, 等.清肝滋肾方对肥胖相关性高血压代谢紊乱的干预作用及其网络药理机制[J].中国实验方剂学杂志, 2022, 28(11):148-155. JIANG Y N, ZHANG S J, HE Y, et al.Effect of Qinggan Zishen prescription on metabolic disorder in obesity-related hypertension and its mechanism based on network pharmacology[J].Chinese Journal of Experimental Traditional Medical Formulae, 2022, 28(11):148-155.(in Chinese) [9] WANG Y, CHU F, LIN J, et al.Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-Akt signaling pathway as revealed by network pharmacology and in vitro experimental verification[J].Journal of Ethnopharmacology, 2021, 279:114399. [10] HAN Y, ZHANG X, KANG Y, et al.Sophoraflavanone M, a prenylated flavonoid from Sophora flavescens Ait., suppresses pro-inflammatory mediators through both NF-κB and JNK/AP-1 signaling pathways in LPS-primed macrophages[J].European Journal of Pharmacology, 2021, 907:174246. [11] LONG G Q, HU G S, GAO X X, et al.Sophoranone A and B:Two new cytotoxic prenylated metabolites and their analogs from the root bark of Sophora flavescens[J].Natural Product Reports, 2022, 36(6):1515-1521. [12] 刘勃兴, 赵安奇, 柳翠翠, 等.犊牛腹泻沙门菌抗菌药敏感性试验与中药体外抑菌试验[J].中国兽医杂志, 2021, 57(3):26-30. LIU B X, ZHAO A Q, LIU C C, et al.Antibiotic susceptibility test of Salmonella diarrhea in calves and in vitro bacteriostasis test of traditional chinese medicine[J].Chinese Journal of Veterinary Medicine, 2021, 57(3):26-30.(in Chinese) [13] 王丹阳, 张康, 王旭荣, 等.诃子、矮紫堇、甘青乌头提取物对牛病毒性腹泻病毒的体外抑制作用[J].畜牧兽医学报, 2018, 49(9):2036-2043. WANG D Y, ZHANG K, WANG X R, et al.Inhibitory effects of extracts from Terminalia chebula, Corydalis hendersoni, Aconitum tanguticum on Bovine viral diarrhea virus in vitro[J]. Chinese Journal of Animal and Veterinary Sciences, 2018, 49(9):2036-2043.(in Chinese) [14] 韩玉文, 李子佳, 于文会, 等.复方诃子口服液抗犊牛大肠杆菌性腹泻的药理作用研究[J].中国畜牧兽医, 2019, 46(1):305-312. HAN Y W, LI Z J, YU W H, et al.Studies on the pharmacological effects of compound Myrobalan oral liquid against Escherichia coli diarrhea in calves[J].China Animal Husbandry & Veterinary Medicine, 2019, 46(1):305-312.(in Chinese) [15] 谢晶, 曹冶, 李琰, 等.17味藏药粗提取物对仔猪细菌性腹泻主要病原菌体外抑菌试验[J].养猪, 2019, 5:109-112. XIE J, CAO Y, LI Y, et al.Experimental research on anti-bacterial efect of 17 Tibetan medicine crude extracts on the pathogens of the bacterial diarrhea in piglets[J].Swine Production, 2019, 5:109-112.(in Chinese) [16] 杨松沛, 黄勇, 石湉, 等.中药新制剂菌痢消颗粒对猪鸡细菌性下痢的疗效观察[J].中国兽药杂志, 2009, 43(4):14-16. YANG S P, HUANG Y, SHI T, et al.Therapeutic efficacy of a new Chinese herbal medicine Junlixiao granule on pig and chicken bacilary dysentery[J]. Chinese Journal of Veterinary Drug, 2009, 43(4):14-16.(in Chinese) [17] QIU L, XIAO C J, SHEN Y, et al.Bioactive hydroxypropionylated glucose derivatives from Astragalus bhotanensis[J].Natural Product Research, 2021, 35(23):5066-5074. [18] KUREK-GÓRECKA A, GÓRECKI M, RZEPECKA-STOJKO A, et al.Bee products in dermatology and skin care[J].Molecules, 2020, 25(3):556. [19] LEE C H, TSAI H Y, CHEN C L, et al.Isoliquiritigenin inhibits gastric cancer stemness, modulates tumor microenvironment, and suppresses tumor growth through glucose-regulated protein 78 downregulation[J].Biomedicines, 2022, 10(6):1350. [20] WU D, WU K, ZHU Q, et al.Formononetin administration ameliorates dextran sulfate sodium-induced acute colitis by inhibiting NLRP3 inflammasome signaling pathway[J].Mediators of Inflammation, 2018, 2018:3048532. [21] WU J, YI J, WU Y, et al.3, 3'-dimethylquercetin inhibits the proliferation of human colon cancer RKO cells through inducing G2/M cell cycle arrest and apoptosis[J].Anti-Cancer Agents in Medicinal Chemistry, 2019, 19(3):402-409. [22] EL-DEMERDASH A A, MENZE E T, ESMAT A, et al.Protective and therapeutic effects of the flavonoid "pinocembrin" in indomethacin-induced acute gastric ulcer in rats:Impact of anti-oxidant, anti-inflammatory, and anti-apoptotic mechanisms[J].Naunyn-Schmiedeberg's Archives of Pharmacology, 2021, 394(7):1411-1424. [23] FUKAI T, MARUMO A, KAITOU K, et al.Anti-Helicobacter pylori flavonoids from licorice extract[J].Life Sciences, 2002, 71(12):1449-1463. [24] CHANG Y, ZHAI L, PENG J, et al.Phytochemicals as regulators of Th17/Treg balance in inflammatory bowel diseases[J].Biomedicine and Pharmacotherapy, 2021, 141:111931. [25] ZHONG J, TAN L, CHEN M, et al.Pharmacological activities and molecular mechanisms of Pulsatilla saponins[J].Chinese Medicine, 2022, 17(1):59. [26] LI X, TANG J, XU J, et al.The inflammation-related gene S100A12 is positively regulated by C/EBPβ and AP-1 in pigs[J].International Journal of Molecular Sciences, 2014, 15(8):13802-13816. [27] PU J, CHEN D, TIAN G, et al.All-trans retinoic acid attenuates Transmissible gastroenteritis virus-induced apoptosis in IPEC-J2 cells via inhibiting ROS-mediated p38 MAPK signaling pathway[J].Antioxidants, 2022, 11(2):345. [28] KIM Y, LEE C.Extracellular signal-regulated kinase (ERK) activation is required for Porcine epidemic diarrhea virus replication[J].Virology, 2015, 484:181-193. [29] SIDO A, RADHAKRISHNAN S, KIM S W, et al.A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis[J].Journal of Nutritional Biochemistry, 2017, 43:11-17. [30] DONG Y, XIA Y, YIN J, et al.Optimization, characteristics, and functions of alkaline phosphatase from Escherichia coli[J].Frontiers in Microbiology, 2021, 12:761189. [31] WANG L, QIAO X, ZHANG S, et al.Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-κB activation[J].Virulence, 2018, 9(1):1685-1698. [32] YAO M, GAO W, YANG J, et al.The regulation roles of miR-125b, miR-221 and miR-27b in porcine Salmonella infection signalling pathway[J].Bioscience Reports, 2016, 36(4):e00375. [33] NI B, BAI F F, WEI Y, et al.Apoptosis induced by lipid-associated membrane proteins from Mycoplasma hyopneumoniae in a porcine lung epithelial cell line with the involvement of caspase 3 and the MAPK pathway[J].Genetics and Molecular Research, 2015, 14(3):11429-11443. [34] WANG J, GONG L, ZHANG W, et al.Wnt/β-catenin signaling pathway inhibits Porcine reproductive and respiratory syndrome virus replication by enhancing the nuclear factor-κB-dependent innate immune response[J].Veterinary Microbiology, 2020, 251:108904. [35] MEHROTRA A, BHUSHAN B, KUMAR A, et al.Characterisation and comparison of immune response mechanisms in an indigenous and a commercial pig breed after classical swine fever vaccination[J].Animal Genetics, 2022, 53(1):68-79. [36] WU Y, ZHANG W, ZHANG L, et al.Characterization of immune pleiotropy of ESR1 gene in pigs[J].Immunogenetics, 2020, 72(8):413-422. [37] BERCIER P, GRENIER D.TNF-α disrupts the integrity of the porcine respiratory epithelial barrier[J].Research in Veterinary Science, 2019, 124:13-17. [38] GAO J, SONG G, SHEN H, et al.Allicin improves intestinal epithelial barrier function and prevents LPS-induced barrier damages of intestinal epithelial cell monolayers[J].Frontiers in Immunology, 2022, 13:847861. [39] NGUYEN-THI H A, PHAM T T, TURCHI B, et al.Characterization of Salmonella spp.isolates from swine:Virulence and antimicrobial resistance[J].Animals, 2020, 10(12):2418. [40] WANG X, HUANG X, YANG Q, et al.TMT labeled comparative proteomic analysis reveals spleen active immune responses during Clostridium perfringens type C infected piglet diarrhea[J].PeerJ, 2022, 10:e13006. |