细粒棘球绦虫抗原B的研究进展

›› 2013, Vol. ›› Issue (5): 181-184.

细粒棘球绦虫抗原B的研究进展

袁维峰¹, 巫剑^1,3, 贾红¹, 侯绍华¹, 郭晓宇¹, 马世春², 朱鸿飞¹

1. 中国农业科学院北京畜牧兽医研究所, 北京 100193;
2. 中国动物疫病预防控制中心, 北京 100125;
3. 新疆维吾尔自治区畜牧科学院兽医研究所, 新疆乌鲁木齐 830000

收稿日期:2012-10-16 出版日期:2013-05-20 发布日期:2013-05-27
通讯作者: 朱鸿飞,研究员,博士生导师。Tel:010-62819364;E-mail:bioclub@vip.sina.com E-mail:bioclub@vip.sina.com
作者简介:袁维峰(1981-),男,江苏人,博士,助理研究员,主要从事牛结核病等人兽共患病的诊断技术与免疫机理研究。巫剑(1984-),男,江苏人,博士生,主要从事棘球蚴病诊断技术研究。袁维峰和巫剑对文章的贡献相同,同为第一作者。
基金资助:
国家高技术研究发展计划(863计划)(2012AA020900);农业部"棘球蚴病综合防控技术集成与示范"项目;中央级公益性科研院所基本科研业务费专项资金项目(2011js-3、2010js-1)。

Review on Antigen B of Echinococcus granulosus

YUAN Wei-feng¹, WU Jian^1,3, JIA Hong¹, HOU Shao-hua¹, GUO Xiao-yu¹, MA Shi-chun², ZHU Hong-fei¹

1. Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Chinese Center for Disease Control and Prevention, Beijing 100125, China;
3. Veterinary Research Institute, Xinjiang Academy of Animal Science, Urumqi 830000, China

Received:2012-10-16 Online:2013-05-20 Published:2013-05-27

摘要/Abstract

摘要： 细粒棘球绦虫抗原B(AgB)是血清学诊断棘球蚴病最重要的抗原,也是目前研究最多的抗原之一。深入研究抗原B对棘球蚴病的血清学诊断、流行病学研究、综合防控和疫苗的研究开发具有重要的意义。文章针对近年来关于抗原B的分子生物学特征、免疫学特性及在人和动物等中间宿主的血清学诊断方面的研究进展进行综述。

关键词: 细粒棘球绦虫; 诊断抗原; 抗原B; 特异性; 敏感性

Abstract: Antigen B (AgB) of Echinococcosis granulose was the most important antigen in the serological diagnosis of hydatid disease. Studies on antigen B of Echinococcosis granulose would promote the development of serological diagnosis agents, epidemiological studies and vaccines to prevent and control of hydatid disease. In this article, the research advances on molecular and immunological characteristics of antigen B and its potential applications on developing diagnosis methods and vaccines were reviewed.

Key words: Echinococcus granulosus; diagnostic antigen; antigen B; specificity; sensitive

中图分类号:

S852.7

袁维峰, 巫剑, 贾红, 侯绍华, 郭晓宇, 马世春, 朱鸿飞. 细粒棘球绦虫抗原B的研究进展[J]. , 2013, (5): 181-184.

YUAN Wei-feng, WU Jian, JIA Hong, HOU Shao-hua, GUO Xiao-yu, MA Shi-chun, ZHU Hong-fei. Review on Antigen B of Echinococcus granulosus[J]. , 2013, (5): 181-184.

参考文献

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