生长激素释放肽及其生物学效应

›› 2012, Vol. 39 ›› Issue (11): 66-69.

生长激素释放肽及其生物学效应

来景辉¹, 范红结²

1. 宿州职业技术学院动物科学系,安徽宿州 234101;
2. 南京农业大学动物医学院,江苏南京 210095

收稿日期:2012-03-30 出版日期:2012-11-20 发布日期:2012-11-22
通讯作者: 范红结,男,教授,博士生导师。E-mail:fhj-68@sohu.com E-mail:fhj-68@sohu.com
作者简介:来景辉(1970-),男,安徽人,副教授,硕士生,研究方向:动物生理与预防兽医学。
基金资助:
安徽省教育厅自然科学基金项目(KJ2008B060);安徽省宿州市科技攻关项目(20107201)。

Recent Advances in Studies on Ghrelin and its Biological Functions

LAI Jing-hui¹, FAN Hong-jie²

1. Department of Animal Science, Suzhou Vocational and Technical College, Suzhou 234101, China;
2. College of Animal Medicine, Nanjing Agricultural University, Nanjing 210095, China

Received:2012-03-30 Online:2012-11-20 Published:2012-11-22

摘要/Abstract

摘要： 生长激素释放肽(Ghrelin)是一种在动物体内广泛存在的生长激素促分泌素受体(GHSR)的内源性配体, Ghrelin与位于下丘脑的GHSR结合后,具有促进生长激素释放、增加食欲、调节消化系统功能及能量代谢等作用。文章就Ghrelin的结构、分布、生物学效应及在畜牧业上的应用前景等方面进行综述,以期促进Ghrelin的进一步深入研究。

关键词: Ghrelin; 生长激素促分泌素; 生物学效应; 展望

Abstract: Ghrelin, a peptide lying widely in animal bodies, is the endogenous ligand for the growth hormone secretagogue receptor(GHSR). Ghrelin, after binding with GHSR in the hypothalamus and pituitary, not only promotes the GH releasing and increases appetite, but also adjusts the functions of digestive system and energy metabolism. This article mainly reviewed the recent developments on structure, distribution and biological effects of ghrelin as well as its potential applications in animal husbandry, which maybe promotes the further research of ghrelin.

Key words: Ghrelin; growth hormone secretagogue; biological function; outlook

中图分类号:

S852.2

来景辉, 范红结. 生长激素释放肽及其生物学效应[J]. , 2012, 39(11): 66-69.

LAI Jing-hui, FAN Hong-jie. Recent Advances in Studies on Ghrelin and its Biological Functions[J]. , 2012, 39(11): 66-69.

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