小肠潘氏细胞防御素在肠道免疫中作用的研究进展

›› 2012, Vol. 39 ›› Issue (10): 166-169.

小肠潘氏细胞防御素在肠道免疫中作用的研究进展

王永胜¹, 杨银凤²

1. 乌兰察布职业学院,内蒙古集宁 012000;
2. 内蒙古农业大学兽医学院,内蒙古呼和浩特 010018

收稿日期:2012-03-13 出版日期:2012-10-20 发布日期:2012-10-19
通讯作者: 杨银凤(1963-),女,内蒙古人,教授,主要从事基础兽医学的教学及研究工作。E-mail: julie1963@163.com;Tel:0471-4310743 E-mail:julie1963@163.com
作者简介:王永胜(1963-),男,内蒙古人,教授,主要从事畜牧兽医学的教学及研究工作。
基金资助:
国家自然基金项目(31160491)。

Research Progress of Functions of The Paneth Cells Defensin during Intestine Immune

WANG Yong-sheng¹, YANG Yin-feng²

1. Ulanqab Vocational College, Jining 012000, China;
2. Veterinary College of Inner Mongolia Agriculture University, Hohhot 010018, China

Received:2012-03-13 Online:2012-10-20 Published:2012-10-19

摘要/Abstract

摘要： 防御素(defensins)是一类低分子质量抗菌肽,广泛地分布于动物和植物界。小肠潘氏细胞防御素是存在于哺乳动物小肠肠腺底部的潘氏细胞颗粒内的一类抗菌肽,是肠道天然屏障的重要组成部分。作者综述了小肠潘氏细胞防御素的分类、分布、分子特征和抗微生物活性及其在肠道免疫中的作用。

关键词: 防御素; 小肠; 潘氏细胞

Abstract: Defensins are a group of small molecular antimicrobial peptides and distribute mostly in animals and plants. The paneth cells defensins are kinds of antimicrobial peptides which have existed in the paneth cells of some mammal’s small intestinal crypts and have important roles in natural immunity of intestinal tract. The classification, distribution, molecular characteristicsm, antimicrobial activities and immune function of paneth cells defensins at home and abroad were summaried.

Key words: defensin; small intestine; paneth cell 

中图分类号:

Q459

王永胜, 杨银凤. 小肠潘氏细胞防御素在肠道免疫中作用的研究进展[J]. , 2012, 39(10): 166-169.

WANG Yong-sheng, YANG Yin-feng. Research Progress of Functions of The Paneth Cells Defensin during Intestine Immune[J]. , 2012, 39(10): 166-169.

参考文献

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