›› 2011, Vol. 38 ›› Issue (3): 128-131.

• 遗传繁育 • 上一篇    下一篇

RNA干扰技术在动物繁殖中的应用

陈娟1,杨永梅1,陈洋1,姜怀志1,杨雨江1,巩俊明2   

  1. (1.吉林农业大学动物科技学院,吉林长春 130118; 2.吉林省双辽市畜牧总站,吉林双辽 136400)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-03-20 发布日期:2011-03-20
  • 通讯作者: 姜怀志

Application of RNA Interference in Animal Breeding

CHEN Juan1,YANG Yong-mei1,CHEN Yang1,JIANG Huai-zhi1,YANG Yu-jiang1,GONG Jun-ming2

  

  1. (1.Department of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China;2.The Animal Husbandry of Shuangliao in Jilin Province,Shuangliao 136400,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-03-20 Published:2011-03-20
  • Contact: JIANG Huai-zhi

摘要:

RNA干扰(RNA interference,RNAi)是一种由双链RNA诱发的转录后水平的基因沉默现象,是近几年发展起来的基因表达调节新机制,广泛地存在于真菌、植物和动物中。到目前为止,已有很多试验证明,RNAi作为一种基因功能研究的新手段,在动物繁殖研究中发挥了极其高效的作用。作者主要介绍了RNAi的研究历史、分子机制、作用特点、生物学意义及在动物繁殖中的应用。

关键词: RNA干扰; 双链RNA; 小干扰RNA; 动物繁殖

Abstract: RNA interference (RNAi) is a phenomenon of post-transcript gene silencing induced by double strand RNA and a new mechanism of regulating gene expressing,which widely exists in epiphyte,plants and animals. So far,a number of tests have proved that RNAi as a new method to study gene function has played a very effective role in studying of animal breeding. This study aimed to introduce the discovery of RNA interference,molecular mechanism,role of the characteristics,the significance of biology and wide application of RNAi in animal breeding.

Key words: RNA interference; double strand RNA; small interfering RNA; animal breeding

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