›› 2010, Vol. 37 ›› Issue (4): 50-52.

• 生理生化 • 上一篇    下一篇

沙葱多糖对小鼠腹腔巨噬细胞的激活作用

王丽思,敖长金,张兴夫   

  1. (内蒙古农业大学动物科学学院, 呼和浩特 010018)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-04-20 发布日期:2010-04-20
  • 通讯作者: 敖长金

Activation of Peritoneal Macrophages by Polysaccharides Extracted from Allium Mongolicum Regel in Mice

WANG Li-si, AO Chang-jin, ZHANG Xing-fu   

  1. (College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-04-20 Published:2010-04-20
  • Contact: AO Chang-jin

摘要: 本试验旨在研究沙葱多糖对小鼠腹腔巨噬细胞的激活作用。采用不同浓度的沙葱多糖培养小鼠腹腔巨噬细胞,测定巨噬细胞的吞噬能力、能量代谢水平、IL-6的含量。结果表明,沙葱多糖能够增强巨噬细胞吞噬能力,提高能量代谢水平,促进IL-6的分泌。除在沙葱多糖对IL-6分泌影响的试验中,沙葱多糖浓度为400 μg/mL时与空白对照组差异不显著(P>0.05),其余测定指标中,试验组各个浓度均显著高于空白对照组(P<0.05)。由试验结果可知,沙葱多糖对小鼠腹腔巨噬细胞具有激活作用。

关键词: 沙葱多糖; 巨噬细胞; 激活作用

Abstract: A study was conducted to evaluate the activation of peritoneal macrophages by polysaccharides extracted from Allium Mongolicum Regel in mice. The peritoneal macrophages were cultured at different concentration of Allium Mongolicum Regel polysaccharides, the phagocytosis capability, energy metabolism level and IL-6 activity were assayed. The results showed that Allium Mongolicum Regel polysaccharides could enhance the phagocytosis capability, energy metabolism level and IL-6 activity. Except the test of IL-6 activity, 400 μg/mL Allium Mongolicum Regel polysaccharides and the blank control group were not significant (P>0.05), in the other index, the test groups were significantly higher than the blank control group (P<0.05). The peritoneal macrophages could be activated by polysaccharides extracted from Allium Mongolicum Regel in mice.

Key words: Allium Mongolicum Regel polysaccharides; macrophage; activation

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