›› 2007, Vol. 34 ›› Issue (4): 93-95.

• 疾病防治 • 上一篇    下一篇

不同比例虫草培养基混合料对SPF级Wistar大鼠主要脏器重量及其系数的影响

袁进,顾为望,林继红,张嘉宁,吴清洪
  

  1. 南方医科大学实验动物中心,广州 510515
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-04-20 发布日期:2007-04-20

Effect of Admixture of Cordyceps Culture Medium of Different Percentage on Main Organ Weight and Organ Coefficients in SPF Wistar Rats

YUAN Jin, GU Weiwang, LIN Jihong, ZHANG Jianing, WU Qinghong
  

  1. Laboratory Animal Center of Southern Medical University, Guangzhou 510515, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-20 Published:2007-04-20

摘要: 为探讨不同比例的虫草培养基混合料对SPF级Wistar大鼠主要脏器重量及脏器系数的影响,用电子天平测定3组动物的体重、心、肝、脾、肺、肾、肾上腺、睾丸、卵巢和胃的重量,并计算其脏器系数。结果表明,不同比例组的同性别Wistar大鼠,其体重之间不存在显著差异;低比例组雄性Wistar大鼠心脏、肺脏和睾丸,雌性Wistar大鼠肺脏的重量显著或极显著高〖JP2〗于对照组、高比例组;低比例组雄性Wistar大鼠心脏、肺脏、肾脏和睾丸,雌性Wistar大鼠心脏、肝脏、肺脏、肾脏和胃的脏器系数显著或极显著高于对照组、高比例组;低、高比例组Wistar雄鼠和高比例组Wistar雌鼠的肾上腺重量及其系数均显著低于对照组。可见,适当比例的虫草培养基可以作为啮齿类试验动物的添加料,但是否适用于饲喂其它动物还有待于进一步的试验研究。

关键词: 虫草培养基混合料; SPF级Wistar大鼠; 脏器系数

Abstract: To research effect of admixture of cordyceps culture medium of different percentage on main organ weight and organ coefficients in SPF Wistar rat. We measured body weight, weight of heart, liver, spleen, lung, kidney, adrenal gland, testicle, ovary and stomach of Wistar rat in each group by electronic scale, and computed their organ coefficients. Results: It do not exist significant difference for body weight of Wistar rat of same sexes among different groups; Organ weight of heart, lung and testicle of males and lung of females in Wistar rat of lowpercentage group are higher remarkably than control group’s and highpercentage group’s; Organ coefficient of of heart, lung, kidney and testicle of males and heart, liver, lung, kidney and stomach of females in Wistar rat of lowpercentage group are higher remarkly than control group’s and highpercentage group’s; Weight and its coefficient of adrenal gland of males of low & highpercentage group and it of female in Wistar rat are notably lower than control group’s. Conclusion: premix of Cordyceps culture medium of suitable percentage can use for basic feed of laboratory animal in rodents, but it is await for farther experimental research whether or not is fit for other animal. 

Key words: admixture of cordyceps culture medium; SPF Wistar rat; organ coefficient

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