[1] 郭思依, 孙明娜, 董旭, 等. 免疫分析技术在农药残留快速检测中的应用及研究进展[J]. 中国农学通报, 2021, 37(23): 106-112. GUO S Y, SUN M N, DONG X, et al. Application and research progress of immunoassay technology in rapid detection of pesticide residues[J]. Chinese Agricultural Science Bulletin, 2021, 37(23): 106-112. (in Chinese) [2] 何扩, 张秀媛, 杜欣军, 等. 基因工程抗体在食品安全检测中应用进展研究[J]. 中国粮油学报, 2014, 29(8): 124-128. HE K, ZHANG X Y, DU X J, et al. Application progress of genetic engineering antibody in food safety testing[J]. Journal of the Chinese Cereals and Oils Association, 2014, 29(8): 124-128. (in Chinese) [3] 于昊天. 全人源抗蓖麻毒素单链抗体制备及其生物学活性研究[D]. 北京: 军事科学院, 2020. YU H T. Preparation of full-human anti-RT single-chain antibody and study on its biological activity[D]. Beijing: Academy of Military Sciences, 2020. (in Chinese) [4] 张泽, 张颖聪, 于洪伟, 等. 生物传感器识别元件的种类及其在临床检验中的研究进展[J]. 临床检验杂志, 2020, 38(10): 767-771. ZHANG Z, ZHANG Y C, YU H W, et al. Biosensor identification elements and their research progress in clinical laboratory[J]. Journal of Clinical Laboratory, 2020, 38(10): 767-771. (in Chinese) [5] 李群林. 分子模拟技术研究吡唑乙基苯甲酰胺衍生物作为食欲素受体1拮抗剂[D]. 上海: 上海应用技术大学, 2020. LI Q L. Molecular modeling technology studies of novel pyrazoylethylbenzamide derivatives as selective orexin oeceptor 1 antagonists[D]. Shanghai: Shanghai Institute of Technology, 2020. (in Chinese) [6] 林婷, 黄义德. 单链抗体在毕赤酵母中表达的研究进展[J]. 生物技术通讯, 2019, 30(5): 693-701. LIN T, HUANG Y D. Research progress of the expression of single-chain variable fragment in Pichia pastoris[J]. Letters in Biotechnology, 2019, 30(5): 693-701. (in Chinese) [7] AGUIAR R B, SILVA T A, COSTA B A, et al. Generation and functional characterization of a single-chain variable fragment (ScFv) of the anti-FGF2 3F12E7 monoclonal antibody[J]. Science Reports, 2021, 11(1): 1432. [8] ChRISTOPH E H, CONSTANT Z M, DOMINIK E, et al. Single-chain antibodies as diagnostic tools and therapeutic agents[J]. Intravascular Biology Meeting, 2008, 101(6): 1012-1019. [9] HE X, DUAN C F, QI Y H, et al. Virtual mutation and directional evolution of anti-amoxicillin ScFv antibody for immunoassay of penicillins in milk[J]. Analytical and Bioanalytical Chemistry, 2017, 517: 9-17. [10] XIE S, WEN K, XIE J, et al. Magnetic-assisted biotinylated single-chain variable fragment antibody-based immunoassay for amantadine detection in chicken[J]. Analytical and Bioanalytical Chemistry, 2018, 410(24): 6197-6205. [11] ZHANG X, HE K, ZHAO R, et al. Cloning of ScFv from hybridomas using a rational strategy: Application as a receptor to sensitive detection microcystin-LR in water[J]. Chemosphere, 2016, 160: 230-236. [12] ZHAO F C, TIAN Y, WANG H M, et al. Development of a biotinylated broad-specificity single-chain variable fragment antibody and a sensitive immunoassay for detection of organophosphorus pesticides[J]. Analytical and Bioanalytical Chemistry, 2016, 408(23): 6423-6430. [13] 尹志安. 猪流行性腹泻病毒野生株CH/JX226/2018的分离培养及抗病毒单链抗体研究[D]. 郑州: 河南农业大学, 2019. YIN Z A. The culture isolation of wild-type PEDV CH/JX226/2018 and the research on anti-PEDV single-chain antibody[D]. Zhengzhou: Henan Agricultural University, 2019. (in Chinese) [14] AHMED S, NING J, CHENG G, et al. Receptor-based screening assays for the detection of antibiotics residues——A review[J]. Talanta, 2017, 166: 176-186. [15] 殷萌琪. α-玉米赤霉醇类化合物和β-内酰胺类抗生素的广谱快速检测方法研究[D]. 无锡: 江南大学, 2020. YIN M Q. Study on broad-spectrum and rapid determination of α-zearalanol compounds and β-lactam antibiotics[D]. Wuxi: Jiangnan University, 2020. (in Chinese) [16] MOON J, KIM G, PARK S B, et al. Comparison of whole-cell SELEX methods for the identification of Staphylococcus aureus-specific DNA aptamers[J]. Sensors, 2015, 15(4): 8884-8897. [17] 崔妍, 白亚龙, 史贤明. 核酸适配体在金黄色葡萄球菌检测中的应用进展[J]. 食品工业科技, 2021, 42(21): 1-7. CUI Y, BAI Y L, SHI X M. Progress on the application of aptamers in the detection of Staphylococcus aureus[J]. Science and Technology of Food Industry, 2021, 42(21): 1-7. (in Chinese) [18] WANG J L, LU T T, HU Y, et al. A label-free and carbon dots based fluorescent aptasensor for the detection of kanamycin in milk[J]. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 2020, 226: 117651. [19] ZON G. Mini-review: Recent advances in aptamer applications[J]. Journal of Cancer Treatment and Diagnosis, 2020, 4(3): 113894 [20] LI F Q, YU Z G, HAN X D, et al. Electrochemical aptamer-based sensors for food and water analysis: A review[J]. Analytica Chimica Acta, 2019, 1051: 1-23. [21] TANG Z Y, JUN Y G, LV Y J, et al. Aptamer-conjugated and doxorubicin-loaded grapefruit-derived nanovectors for targeted therapy against HER2+ breast cancer[J]. Journal of Drug Targeting, 2020, 28(2): 186-194. [22] 刘蕊, 农药特异性基因工程抗体的分子设计、表达及识别机制[D]. 杭州: 浙江大学, 2016. LIU R. Molecular design expression and recongnition mechanism of engingeering antibodies against pesticides[D]. Hangzhou: Zhejiang University, 2016. (in Chinese) [23] 陈烨. 基于群智能算法的蛋白质结构预测研究[D]. 北京: 中国矿业大学, 2018. CHEN Y. Study on the protein structure prediction based on swarm intelligence algorithm[D]. Beijing: China University of Mining and Technology, 2018. (in Chinese) [24] 仝泽方. 通过氨基酸定点突变调控水稻OsHAL3蛋白功能的研究[D]. 沈阳: 沈阳农业大学, 2018. TONG Z F. Regulation of the OsHAL3 protein function by site-directed mutagenesis of amino acids[D]. Shenyang: Shenyang Agricultural University, 2018. (in Chinese) [25] 王鸽. 四环素类药物受体的制备及进化[D]. 保定: 河北农业大学, 2020. WANG G. Preparation and directional evolution of the receptor of tetracyclines[D]. Baoding: Hebei Agricultural University, 2020. (in Chinese) [26] 成胜荣. 同源异效桑源药材(桑叶、桑枝、桑白皮、桑椹)的物质基础研究[D]. 镇江: 江苏大学, 2019. CHENG S R. Study on the material basis of homologous and heterologous mulberry medicinal materials (mulberry leaves, mulberry branches, mulberry white skin and mulberry)[D]. Zhenjiang: Jiangsu University, 2019. (in Chinese) [27] LIU Y H, JIN M J, GUI J W, et al. Hapten design and indirect competitive immunoassay for parathion determination: Correlation with molecular modeling and principal component analysis[J]. Analytical and Bioanalytical Chemistry, 2007, 591(2): 173-182. [28] LIU M, ZHENG N, LI D, et al. Cyp51A-based mechanism of azole resistance in Aspergillus fumigatus: Illustration by a new 3D structural model of Aspergillus fumigatus CYP51A protein[J]. Medical Mycology, 2016, 54(4): 400-408. [29] 宋亚宁, 胡超琼, 王冲, 等. 核酸适配体生物传感器在食品中氟喹诺酮类兽药残留检测中的应用[J]. 中国食品学报, 2021, 21(8): 409-419. SONG Y N, HU C Q, WANG C, et al. Application of aptamer biosensor in the determination of fluoroquinolones residues in food[J]. Journal of Chinese Institute of Food Science and Technology, 2021, 21(8): 409-419. (in Chinese) [30] WANG J P, DONG J, DUAN C F, et al. Production and directional evolution of antisarafloxacin ScFv antibody for immunoassay of fluoroquinolones in milk[J]. Agricultural Food Chemistry, 2016, 64(42): 7957-7965. [31] 曹子健, 何欣, 王建平, 等. 抗沙拉沙星ScFv同源模拟及分子结合机制[J]. 黑龙江畜牧兽医, 2018, 1: 47-51. CAO Z J, HE X, WANG J P, et al. Homology modeling of anti-salafloxacin ScFv antibody and the mechanism of molecular binding[J]. Heilongjiang Animal Science and Veterinary Medicine, 2018, 1: 47-51. (in Chinese) [32] ZHANG X Y, HE K, ZHANG D H, et al. Production and characterization of a monoclonal antibody for pefloxacin and mechanism study of antibody recognition[J]. Bioscience, Biotechnology, and Biochemistry, 2019, 83(4): 633-640. [33] WEN K, NOLKE G, SCHILLBERG S, et al. Improved fluoroquinolone detection in ELISA through engineering of a broad-specific single-chain variable fragment binding simultaneously to 20 fluoroquinolones[J]. Analytical and Bioanalytical Chemistry, 2012, 403(9): 2771-2783. [34] 董文婷, 曾勇, 吴晓翠, 等. 液相色谱-串联质谱法测定禽蛋中β-内酰胺类药物残留[J]. 食品安全质量检测学报, 2020, 11(20): 7582-7590. DONG W T, ZENG Y, WU X C, et al. Determination of β-lactam in poultry eggs by liquid chromatography tandem mass spectrometry[J]. Journal of Food Safety and Quality, 2020, 11(20): 7582-7590. (in Chinese) [35] 王俊豪, 丛萌, 陶燕飞, 等. 鸡蛋中抗菌药物残留消除规律研究进展[J]. 中国抗生素杂志, 2020, 45(12): 1208-1220. WANG J H, CONG M, TAO Y F, et al. Research progress on elimination of antimicrobial residues in eggs[J]. Chinese Journal of Antibiotics, 2020, 45(12): 1208-1220. (in Chinese) [36] LIU J, ZHANG H C, DUAN C F, et al. Production of anti-amoxicillin ScFv antibody and simulation studying its molecular recognition mechanism for penicillins[J]. Environmental Science and Health B, 2016, 51(11): 742-750. [37] 段长飞. 阿莫西林单链抗体的定向进化[D]. 保定: 河北农业大学, 2017. DUAN C F. Directional evolution of the anti-amoxicillin single chain antibody fragment[D]. Baoding: Hebei Agricultural University, 2017. (in Chinese) [38] XIE S L, WANG J Y, YU X Z, et al. Site-directed mutations of anti-amantadine ScFv antibody by molecular dynamics simulation: Prediction and validation[J]. Molecular Modeling, 2020, 26(3): 49. [39] LI L, HOU R, WANG X Q, et al. Development of a monoclonal-based ic-ELISA for the determination of kitasamycin in animal tissues andsimulation studying its molecular recognition mechanism[J]. Food Chemistry, 2021, 363: 129465. [40] 史芳舒. 吩噻嗪类药物单链抗体的制备及进化[D]. 保定: 河北农业大学, 2018. SHI F S. Preparation and directional evolution of the anti-phenothiazines single chain antibody fragment[D]. Baoding: Hebei Agricultural University, 2018. (in Chinese) [41] LU Q, HOU Y Y, LIU X X, et al. Construction, expression and functional analysis of anti-clenbuterol codon-optimized ScFv recombinant antibody[J]. Food Chemical Toxicology, 2020, 135: 110973. [42] LIANG X, LI C, ZHU J, et al. Dihydropteroate synthase based sensor for screening multi-sulfonamides residue and its comparison with broad-specific antibody based immunoassay by molecular modeling analysis[J]. Analytica Chimica Acta 2019, 1050: 139-145. [43] NING J N, AHMED S, CENG G Y, et al. Analysis of the stability and affinity of BlaR-CTD protein to β-lactam antibiotics based on docking and mutagenesis studies[J]. Biological Engineering, 2019, 13: 27. [44] WANG G, ZHANG H C, LIU J, et al. A receptor-based chemiluminescence enzyme linked immunosorbent assay for determination of tetracyclines in milk[J]. Analytical Biochemistry, 2019, 564-565: 40-46. [45] WANG G, XIA W Q, LIU J X, et al. Directional evolution of TetR protein and development of a fluoroimmunoassay for screening of tetracyclines in egg[J]. Microchemical Journal, 2019, 150: 104184. [46] ZHANG J, ZHANG T H, GUAN T Z, et al. Spectroscopic and molecular modeling approaches to investigate the interaction of bisphenol A, bisphenol F and their diglycidyl ethers with PPARα[J]. Chemosphere, 2017, 180: 253-258. [47] GUAN T Z, SUN Y H, WANG Y J, et al. Multi-residue method for the analysis of stilbene estrogens in milk[J]. Molecular Sciences, 2019, 20(3): 44. [48] RAZA M, AHMAD A, YUE F, et al. Biophysical and molecular docking approaches for the investigation of biomolecular interactions between amphotericin B and bovine serum albumin[J]. Photochemistry and Photobiology. B, Biology, 2017, 170: 6-15. [49] ZHAO T, LIU Z H, NIU J M, et al. Investigation of the interaction mechanism between salbutamol and human serum albumin by multispectroscopic and molecular docking[J]. BioMed Research International, 2020, 2020: 1693602. [50] MENG X Y, ZHANG H X, MEZEI M, et al. Molecular docking: A powerful approach for structure-based drug discovery[J]. Current Computer-Aided Drug Design, 2011, 7(2): 146-157. [51] SONG M C, LIM S J, TONG J C. Recent advances in computer-aided drug design[J]. Briefings in Bioinformatics, 2009, 10(5): 579-591. [52] YANG J T, LI Q, BIAN L J. Spectroscopic analysis and docking simulation on the recognition and binding of TEM-1 β-lactamase with β-lactam antibiotics[J]. Experimental and Therapeutic Medicine, 2017, 14: 3288-3298. [53] LI Q, ZHANG T L, BIAN L J. Recognition and binding of β-lactam antibiotics to bovine serum albumin by frontal affinity chromatography in combination with spectroscopy and molecular docking[J]. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 2016, 1014: 90-101. [54] 梁晓. 基于二氢叶酸合成酶的磺胺类药物多残留快速检测分析研究[D]. 北京: 中国农业大学, 2014. LIANG X. Development of rapid detection methods based on dihydropteroate synthase for sulfonamides[D]. Beijing: China Agricultural University, 2014. (in Chinese) [55] 关天竺. 基于雌激素受体的双酚类化合物检测方法及构效关系研究[D]. 长春: 吉林大学, 2019. GUAN T Z. Estrogen receptor-based multi-residue screening of bisphenol compounds and structure-activity relationships studies[D]. Changchun: Jilin University, 2019. (in Chinese) [56] ZHANG Q, NI Y. Comparative studies on the interaction of nitrofuran antibiotics with bovine serum albumin[J]. Royal Society of Chemistry, 2017, 7(63): 39833-39841. [57] PENG W, DING F, PENG Y K, et al. Molecular recognition of malachite green by hemoglobin and their specific interactions: Insights from in silico docking and molecular spectroscopy[J]. Molecular BioSystems, 2014, 10(1): 138-148. [58] LI Z, BO P, ZHANG H M. Investigation on the interaction between an antimicrobial in aquaculture, malachite green and hemocyanin from mud crab Scylla paramamosain[J]. Molecular and Biomolecular Spectroscopy, 2015, 135: 669-675. [59] 韩旭艳. 氨基糖苷类抗生素特异性单链DNA适配体的筛选及其应用研究[D]. 无锡: 江南大学, 2018. HAN X Y. Selection and application of aminoglycoside antibiotics-specific single-stranded DNA aptamers[D]. Wuxi: Jiangnan University, 2018. (in Chinese) [60] SADEGHI A S, MOHSENZADEH M, ABNOUS K, et al. Development and characterization of DNA aptamers against florfenicol: Fabrication of a sensitive fluorescent aptasensor for specific detection of florfenicol in milk[J]. Talanta, 2018, 182: 193-201. [61] YANG L, NI H J, LI C L, et al. Development of a highly specific chemiluminescence aptasensor for sulfamethazine detection in milk based on in vitro selected aptamers[J]. Sensors and Actuators B: Chemical, 2019, 281: 801-811. [62] 邹雪梅. 阿米卡星适配体的筛选及在残留检测中的应用[D]. 镇江: 江苏大学, 2018. ZOU X M. Selection of amikacin aptamer and its application in the detection of amikacin residue[D]. Zhenjiang: Jiangsu University, 2018. (in Chinese) [63] 张玉红. 妥布霉素特异性单链DNA适配体的筛选及其序列优化和应用研究[D]. 无锡: 江南大学, 2017. ZHANG Y H. Selection and sequence optimization of tobamycin specific single stranded DNA aptamers and their applications[D]. Wuxi: Jiangnan University, 2017. (in Chinese) [64] EISOLD A, LABUDDE D. Detailed analysis of 17β-estradiol-aptamer interactions: A molecular dynamics simulation study[J]. Molecules, 2018, 23(7): 1690. |