产后酮病奶牛血液生化指征分析

doi:10.16431/j.cnki.1671-7236.2020.06.010

中国畜牧兽医 ›› 2020, Vol. 47 ›› Issue (6): 1719-1728.doi: 10.16431/j.cnki.1671-7236.2020.06.010

产后酮病奶牛血液生化指征分析

郭仕辉¹, 余永涛¹, 赵清梅^2,3, 许立华¹, 万佳宏¹, 何生虎¹, 杨奇⁴, 李柯¹

1. 宁夏大学农学院, 银川 750021;
2. 北方民族大学生物科学与工程学院, 银川 750021;
3. 国家民委发酵酿造工程生物技术重点实验室, 银川 750021;
4. 宁夏回族自治区兽药饲料监察所, 银川 750011

收稿日期:2019-12-10 出版日期:2020-06-20 发布日期:2020-06-20
通讯作者: 余永涛 E-mail:yyt1211@163.com
作者简介:郭仕辉(1995-),男,河南平顶山人,硕士生,研究方向:动物营养代谢病,E-mail:15093775627@163.com
基金资助:
宁夏回族自治区重点研发计划项目（2019NYYZ0503）；国家自然科学基金（31560713、31960348）

Monitoring of Blood Biochemical Indicators in Ketosis Cattle

GUO Shihui¹, YU Yongtao¹, ZHAO Qingmei^2,3, XU Lihua¹, WAN Jiahong¹, HE Shenghu¹, YANG Qi⁴, LI Ke¹

1. School of Agricuture Ningxia University, Yinchuan 750021, China;
2. College of Biological Science and Engineering, North Minzu University, Yinchuan 750021, China;
3. Key Laboratory of Fermentation Brewing Engineering and Biotechnology State Nationalities Affairs Commission, Yinchuan 750021, China;
4. Veterinary Drug and Feed Monitoring Institute of Ningxia Hui Autonomous Region, Yinchuan 750011, China

Received:2019-12-10 Online:2020-06-20 Published:2020-06-20

摘要/Abstract

摘要： 为了比较产后一段时期内酮病奶牛与健康奶牛血液生化指标的差异，为奶牛酮病的防控及兽医临床诊治提供理论依据。本研究选取吴忠市某集约化奶牛场待产奶牛共30头进行为期3周的血液生化指标监测，根据β-羟丁酸（BHBA）的浓度将奶牛分为酮病组和对照组并进行比较研究。结果显示，酮病组与对照组在生产当天（0 d）各项检测指标未出现显著性差异；酮病组奶牛β-羟丁酸浓度在产后7 d时较对照组极显著升高（P<0.01）；天门冬氨酸氨基转移酶（AST）和总胆红素（T-bil）浓度在产后7 d和14 d时显著升高（P<0.05）；血糖（Glu）浓度在产后7 d时显著降低（P<0.05），产后14 d时极显著降低（P<0.01）；钙（Ca）、磷（P）浓度无显著性差异，但均低于正常参考值范围，出现低血钙、低血磷症。经分析发现，本场奶牛所患酮病为Ⅱ型酮病，酮病牛高发胎次为3~6胎，产后低血钙、低血磷、低血糖现象严重，同时奶牛酮病引发了机体肝脏功能损伤，影响母牛生产性能。

关键词: 奶牛酮病; β-羟丁酸; 肝脏功能; 低血钙症; 低血糖症

Abstract: In order to compare the difference of blood biochemical indexes between ketosis dairy cows and healthy dairy cows in a period of postpartum,and provide theoretical basis for prevention and control of ketosis dairy cows and veterinary clinical diagnosis and treatment.In this study,30 cows in an intensive dairy farm in Wuzhong city were selected for blood biochemical monitoring for 3 weeks.Dairy cows were divided into ketosis group and control group according to the concentration of β-hydroxybutyric acid (BHBA) which be used to compare significance.The results showed that there was no significant difference between the ketosis group and the control group on the day of calving (0 d);The concentration of BHBA in the ketosis group was extremely significantly higher than that in the control group on the 7th postnatal day (P<0.01);The concentrations of AST and T-bil were significantly higher on the 7th and 14th postnatal day (P<0.05);The concentrations of blood glucose (Glu) decreased significantly at 7th postpartum (P<0.05),and it decreased extremely significantly on the 14th postpartum (P<0.01);The concentrations of calcium (Ca) and phosphorus (P) did not show significant differences,but both were lower than the normal reference range which resulted in hypocalcemia and hypophosphatemia.It was found that the ketosis of dairy cows in this field was type Ⅱ ketosis after analysis and the high parity of ketosis cattle was 3-6 parities and the postpartum hypocalcemia,hypophosphatemia,and hypoglycemia were serious.At the same time,cow ketosis could cause hepatic dysfunction and affect cow performance.

Key words: cow ketosis; β-hydroxybutyrate; liver function; hypocalcemia; hypoglycemia

中图分类号:

S856.5

郭仕辉, 余永涛, 赵清梅, 许立华, 万佳宏, 何生虎, 杨奇, 李柯. 产后酮病奶牛血液生化指征分析[J]. 中国畜牧兽医, 2020, 47(6): 1719-1728.

GUO Shihui, YU Yongtao, ZHAO Qingmei, XU Lihua, WAN Jiahong, HE Shenghu, YANG Qi, LI Ke. Monitoring of Blood Biochemical Indicators in Ketosis Cattle[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(6): 1719-1728.

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产后酮病奶牛血液生化指征分析

Monitoring of Blood Biochemical Indicators in Ketosis Cattle

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