夏、冬两季猪源葡萄球菌耐药情况比较

doi:10.16431/j.cnki.1671-7236.2017.05.039

《中国畜牧兽医》 ›› 2017, Vol. 44 ›› Issue (5): 1541-1546.doi: 10.16431/j.cnki.1671-7236.2017.05.039

夏、冬两季猪源葡萄球菌耐药情况比较

蔡建星, 郭庆勇, 刘英玉, 夏利宁, 轩慧勇, 林亚军, 江萍

新疆农业大学动物医学学院, 乌鲁木齐 830052

收稿日期:2016-11-10 出版日期:2017-05-20 发布日期:2017-05-18
通讯作者: 夏利宁 E-mail:xln750530@163.com
作者简介:蔡建星(1991-),女,新疆乌鲁木齐人,硕士生,研究方向:兽医药理与毒理学,E-mail:cjx609231608@163.com
基金资助:
新疆维吾尔自治区科技厅自然科学基金项目（2014211A030）

Comparing the Resistance of Staphylociccus Isolated from Pigs to Antimicrobial Drugs in Summer and Winter

CAI Jian-xing, GUO Qing-yong, LIU Ying-yu, XIA Li-ning, XUAN Hui-yong, LIN Ya-jun, JIANG Ping

College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China

Received:2016-11-10 Online:2017-05-20 Published:2017-05-18

摘要/Abstract

摘要：

本研究旨在比较夏、冬两季某规模化养猪场猪源葡萄球菌的耐药情况。分别在夏、冬两季对猪场同一猪采集其直肠肛拭子样和鼻腔鼻拭子样，采用微量肉汤稀释法对分离出的葡萄球菌进行临床9种常用抗菌药物的药敏试验。结果显示，夏季鼻腔分离的葡萄球菌对阿米卡星、氟苯尼考、氧氟沙星、苯唑西林和克林霉素5种抗菌药物的耐药率均高于冬季分离的鼻腔菌。夏季直肠分离的葡萄球菌对阿莫西林/克拉维酸、苯唑西林、庆大霉素、氧氟沙星、四环素、克林霉素和利福平7种抗菌药物的耐药率低于冬季分离的直肠菌。且夏、冬两季鼻腔分离的葡萄球菌多药耐药种数在0~9耐均有分布，夏、冬两季直肠分离的葡萄球菌多药耐药种数在1~9均耐有分布。冬季鼻腔分离的葡萄球菌6耐的多药百分率显著高于夏季分离菌的多药百分率（P＜0.05），冬季直肠分离的葡萄球菌8耐的多药百分率显著高于夏季分离菌的多药百分率（P＜0.05）。结果表明，夏、冬两季猪不同部位分离的葡萄球菌对大多数被检抗菌药物的耐药率情况不同，其耐药率与养殖场季节性用药呈现相关性。

关键词: 夏、冬两季; 猪源葡萄球菌; 耐药率

Abstract:

In this study, the resistance of swine Staphylococcus isolated in summer and winter was compared. The rectal anal swab samples and nasal swab samples were collected from the same pig in summer and winter. The susceptibility test of 9 kinds of antimicrobial drugs was carried out by using the broth dilution method. The results revealed that the resistance rates of Staphylococcus isolated from the rectum in summer were higher than that of Staphylococcus isolated from the rectum in winter to amikacin, florfenicol, levofloxacin, benzene and clindamycin. Resistance rates of Staphylococcus isolates from nasal cavity in summer were lower than that of Staphylococcus isolates from nasal cavity in winter to amikacin, benzene, gentamicin, levofloxacin, tetracycline, clindamycin and rifampicin. And Staphylococcus in two seasons in 0 to 9 resistant rectal separation resistance were distributed. Multi drug resistant Staphylococcus in two seasons in 1 to 9 resistant rectal separation resistance were distributed. And in the 6 resistance, the resistance rate of Staphylococcus isolated from the nasal in summer was significantly higher than that of the isolated from anal in winter (P< 0.05). And in 8 resistance, the resistance rate of Staphylococcus isolated from the rectum cavity in summer was significantly higher than that of Staphylococcus isolated from the rectum cavity in winter (P< 0.05). Results showed that the resistance rates of Staphylococcus isolated from different sites of the pigs to the tested antimicrobial drugs were different. The drug resistance rate was correlated with seasonal use of the farm.

Key words: summer and winter; swineStaphylococcus; resistance rate

中图分类号:

R378.11

蔡建星, 郭庆勇, 刘英玉, 夏利宁, 轩慧勇, 林亚军, 江萍. 夏、冬两季猪源葡萄球菌耐药情况比较[J]. 《中国畜牧兽医》, 2017, 44(5): 1541-1546.

CAI Jian-xing, GUO Qing-yong, LIU Ying-yu, XIA Li-ning, XUAN Hui-yong, LIN Ya-jun, JIANG Ping. Comparing the Resistance of Staphylociccus Isolated from Pigs to Antimicrobial Drugs in Summer and Winter[J]. , 2017, 44(5): 1541-1546.

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夏、冬两季猪源葡萄球菌耐药情况比较

Comparing the Resistance of Staphylociccus Isolated from Pigs to Antimicrobial Drugs in Summer and Winter

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