Abstract: In order to compare the resistance of E.coli from pigs of different regions under same breeding mode in Xinjiang, we collected fecal samples from pig farms of Hutubi (207), Manasi (210) and Changji (210) in a certain scale, respectively, a total of 627 samples, and isolation rate of E.coli from fecal samples were all 100.0%.The broth dilution method was used to detect resistance of E.coli to antimicrobials, and we compared the differences of resistance rate of E.coli from pig farms in three regions by chi square test. E.coli from pig farms of Hutubi region to apramycin, amikacin, amoxicillin-clavulanic acid and ceftiofur existed extremely significant differences comparing with another two regions (P< 0.01).E.coli from pig farms of Manasi region to ciprofloxacin existed significant differences comparing with another two regions (P< 0.05), and existed extremely significant differences to norfloxacin (P< 0.01).E.coli from pig farms of Changji region to norfloxacin had extremely significant differences comparing with Hutubi region (P< 0.01), and existed significant differences to amoxicillin-clavulanic acid and ampicillin comparing with Manasi region (P< 0.05).3 to 8 resistant E.coli strains accounted for 94.7% in Hutubi region, 3 to 7 resistant E.coli strains accounted for 89.5% in Manasi region and 4 to 8 resistant E.coli strains accounted for 82.4% in Changji region, respectively.There was no significant difference among different regions on multi-drug resistance (P> 0.05).The results indicated that E.coli from pigs of different regions under the same breeding mode had different characteristics of resistance.In addition, the resistance of E.coli from pigs were very serious and mainly multi-drug resistant, drug resistance patterns were diversified.

Key words: same breeding mode; different regions; E.coli from pig; antimicrobials; resistance rates