RNA干扰及其抗口蹄疫病毒复制的研究进展

›› 2009, Vol. 36 ›› Issue (7): 197-201.

• 流行病防治 • Previous Articles Next Articles

RNA Interference and its Application in FMDV

CHEN Qi-wei^1,2, WANG Yong-lu¹

(1.Key Laboratory of Animal Virology of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China;2.College of Veterinary Medicine Gansu Agricultural University, Gansu 730070, China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-07-20 Published:2009-07-20

Abstract

Abstract: RNA interference refers to the inhibition of gene expression by dsRNA. RNAi has been proved as an antiviral mechanism in plants and insects instead of animals， people made great efforts to establish an efficaciously antiviral strategy in mammalians and have gained many exciting results. At present, although there is more to RNAi than we can yet fathom, it has been extensively used as a reverse genetic tool to explore gene function as well as a therapeutic strategy against important human genetic diseases or viral diseases. Here we wish to review the mechanism of RNAi and its use in FMDV.

Key words: RNA interference(RNAi); FMDV; replication inhibition

CLC Number:

CHEN Qi-wei;WANG Yong-lu. RNA Interference and its Application in FMDV[J]. , 2009, 36(7): 197-201.

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RNA Interference and its Application in FMDV

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