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Research Progress on Porcine Reproductive and Respiratory Syndrome Virus and its Vaccines

TAN Wei, DENG Xian-wen, XIE Zhi-xun   

  1.  (Guangxi Key Laboratory of Animal Vaccines and Diagnosis, Guangxi Veterinary Research Institute, Nanning 530001, China)

  • Revised:2014-02-26 Online:2014-06-20 Published:2014-07-24

Abstract: Porcine reproductive and respiratory syndrome (PRRS) severely affects prosperity of swine industry, and results in enormous economic losses every year. Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS. Pregnant sows infected with PRRSV may suffer from early farrow, abortion or stillbirth, and newborn piglets may develop respiratory symptoms. Although at present inactivated and live-attenuated PRRS vaccines are commercially available, their protective effects are not ideal. Therefore, study on PRRSV gene structure, protein functions, biological characteristics, and pathogenesis will facilitate research and development of safe and effective PRRS vaccines. This article will introduce research progress on PRRSV and its vaccines.

Key words:

porcine reproductive and respiratory syndrome (PRRS); vaccine; porcine reproductive and respiratory syndrome virus (PRRSV)