宏基因组学及其应用前景

Metagenomics and its Application Prospect

Siriguleng Yu¹^{, 2, 3}, Temulun², MING Liang², YI Li², Jirimutu²^{, 3}

(1.Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Science, Inner Mongolia Agricultural University, Hohhot 010018, China; 2. Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China; 3. Inner Mongolia Camel Protection Association, Hohhot 010018, China)

Received:2013-08-15 Online:2014-03-20 Published:2014-05-15

Abstract

Abstract: Metagenomics is the study of communities of microbial organisms directly in their natural environments, bypassing the need for isolation and laboratory cultivation of individual species and showing strong vitality in research of the metabolic pathway and exploring the resource of rumen microbiota. There are abundance of symbiotic microbiota in the gastrointestinal tract of animals, and they are deeply associated with the well-being of the host because of affecting normal physiology, metabolism and health, as well as the development of diseases. The application of metagenomics may solve many hot and difficult issues in the research of ruminant metabolism, especially camel metabolism. Therefore, this paper reviews the construction and selection procedures, especially introduced the Roche454 and Illumina high-throughput sequencing methods. Meanwhile, the application prospects of metagenomic in communities of microbial organisms are explored.

Siriguleng Yu, Temulun, MING Liang, YI Li, Jirimutu. Metagenomics and its Application Prospect[J]. .

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