Abstract: The analysis of pesticides in food and environmental samples is an important part of monitoring the condition of the environment. Gel permeation chromatography (GPC) is a convenient technique to separate small molecules from high molecular weight organic matrices.In this application, eight organochlorine pesticides residues in fresh cream are cleaned up by a GPC system using Agilent EcoSpheres material and then determined by GC-ECD. DB-35ms Ultra Inert capillary GC column and Ultra Inert inlet liner are employed and provide excellent peak shape for this trace-level pesticides analysis. The linearity ranges from 0.9981 to 0.9996 over the concentration of 10~800 ng/mL. RSD were 1.83% to 7.92%.Method recovery and LOD are 92.4%~117.0% and 0.65 ~2.33 μg/kg, respectively.

Key words: GPC; fresh cream; organochlorine pesticide residue; Ultra Inert