Abstract: To evaluate epidemic station of canine influenza virus infection in Guangdong, and provide reference basis for the prevention of canine influenza, 1440 canine serum samples from six different cities in Guangdong province were detected for the level of antibody by enzyme-linked immunosorbent assay (ELISA) and hemagglutination inhibition (HI) assay. The results showed that the average positive rates were 7.92% (ELISA) and 6.25% (HI), and the levels of antibody in Guangzhou, Shenzhen and Huizhou were higher than the other regions. The positive rate was highest in canines of 1 to 3 years old, and the morbidity of the canine influenza was higher in male canines. The results demonstrated that canine influenza virus infection was prevalent in parts of area of Guangdong and avian origin canine influenza virus H3N2 stubtype was the main type.

Key words: canine influenza; serology; investigation