Abstract: This experiment aims to investigate Chinese medicinal compound polysaccharide’s influence on mice immunocompetence with different components and different purities. Cyclophosphamide is used as immunity-inhibition agent to build low immunity animal pattern, which leads to the determination of peritoneal macrophage’s phagocytosis in mice and of organic index of immunity organs. The result shows that polysaccharide component A2 and polysaccharide B2 with average purity can dramatically improve peritoneal macrophage’s phagocytosis in the group of normal mice and in the immunity-inhibition mice group. These two polysaccharides can also enhance thymus index and spleen index and can reverse immunity inhibition caused by cyclophosphamide to normal level. Therefore it is sound to say that polysaccharide components with appropriate molecular weights and polysaccharide with appropriate purity can greatly improve mice’s immunity.

Key words: polysaccharide with different components; polysaccharide with different purities; immunity-inhibition pattern; immunocompetence