Abstract: 120 newborn piglets of Yorkshire were selected in 3 groups randomly. Group A was control and added to physiological saline. Others were added to different amount of IgG in 24 hour to determine the effect of IgG from bovine colostrum on serum IgG of both bovine and piglet and body weight gains in weaning age in 5 and 10 day. The results showed that serum IgG of both bovine and piglet in 5 and 10 day and the body weight grain in weaning age of piglets feeding IgG of 4g were more higher than control group(P<0.05).