Abstract: The foot-and-mouth disease is one kind of important person livestockal together contracts the infectious disease, may cause in the worldscope the animal husbandry to suffer the serious economic loss, the hindrance animal husbandry, the livestock product processing industry development, and harm human body health. The various countries has all adopted the occurrence which the many kinds of measures control should get sick. But guards against the system foot-and-mouth disease the important link is must make the prompt accurate diagnosis. This article diagnoses the engineering research to the foot-and-mouth disease to progress, has carried on the summary including the ELISA diagnosis engineering research as well as the molecular biology diagnosis engineering research progress, and diagnosed the technology to the foot-and-mouth disease to carry on the forecast.