China Animal Husbandry and Veterinary Medicine ›› 2023, Vol. 50 ›› Issue (7): 2931-2940.doi: 10.16431/j.cnki.1671-7236.2023.07.033
• Preventive Veterinary Medicine • Previous Articles Next Articles
LU Sijia, ZHENG Lanlan
Received:
2023-02-24
Published:
2023-06-30
CLC Number:
LU Sijia, ZHENG Lanlan. Research Progress on Porcine Epidemic Diarrhea Virus Vaccines[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(7): 2931-2940.
[1] SUN R Q, CAI R J, CHEN Y Q, et al.Outbreak of porcine epidemic diarrhea in suckling piglets, China[J].Emerging Infectious Diseases, 2012, 18(1):161-163. [2] YUAN C, ZHANG P, LIU P, et al.A novel pathway for Porcine epidemic diarrhea virus transmission from sows to neonatal piglets mediated by colostrum[J].Journal of Virology, 2022, 96(14):e0047722. [3] WANG D, FANG L, XIAO S.Porcine epidemic diarrhea in China[J].Virus Research, 2016, 226:7-13. [4] 刘孝珍, 陈建飞, 时洪艳, 等.2011年猪流行性腹泻病毒的遗传变异分析[J].中国预防兽医学报, 2012, 34(3):180-183. LIU X Z, CHEN J F, SHI H Y, et al.Genetic variation analysis of Porcine epidemic diarrhea virus isolated in 2011[J].Chinese Journal of Preventive Veterinary Medicine, 2012, 34(3):180-183.(in Chinese) [5] KIM S H, LEE J M, JUNG J, et al.Genetic characterization of Porcine epidemic diarrhea virus in Korea from 1998 to 2013[J].Archives of Virology, 2015, 160(4):1055-1064. [6] HUANG Y W, DICKERMAN A W, PINEYRO P, et al.Origin, evolution, and genotyping of emergent Porcine epidemic diarrhea virus strains in the United States[J].mBio, 2013, 4(5):e00737-13. [7] PASICK J, BERHANE Y, OJKIC D, et al.Investigation into the role of potentially contaminated feed as a source of the first-detected outbreaks of porcine epidemic diarrhea in Canada[J].Transboundary and Emerging Diseases, 2014, 61(5):397-410. [8] LI C, LU H, GENG C, et al.Epidemic and evolutionary characteristics of swine enteric viruses in South-Central China from 2018 to 2021[J].Viruses, 2022, 14(7):1420. [9] NIU X, WANG Q.Prevention and control of porcine epidemic diarrhea:The development of recombination-resistant live attenuated vaccines[J].Viruses, 2022, 14(6):1317. [10] 左媛媛, 徐天刚, 戈胜强, 等.我国猪流行性腹泻病毒流行现状及分子遗传演化特征[J].中国动物检疫, 2022, 39(9):9-17. ZUO Y Y, XU T G, GE S Q, et al.Prevalence and molecular genetic evolution of Porcine epidemic diarrhea virus in China[J]. China Animal Health Inspection, 2022, 39(9):9-17.(in Chinese) [11] GUO J, FANG L, YE X, et al.Evolutionary and genotypic analyses of global Porcine epidemic diarrhea virus strains[J].Transboundary and Emerging Diseases, 2019, 66(1):111-118. [12] 王明, 马思奇, 周金法, 等.猪流行性腹泻灭活疫苗的研究[J].中国畜禽传染病, 1993, 5:17-19. WANG M, MA S Q, ZHOU J F, et al.Study on inactivated vaccine of porcine epidemic diarrhea[J].China Infectious Diseases of Livestock and Poultry, 1993, 5:17-19.(in Chinese) [13] 马思奇, 王明, 周金法, 等.猪流行性腹泻病毒适应Vero细胞培养及以传代细胞毒制备氢氧化铝灭活疫苗免疫效力试验[J].中国畜禽传染病, 1994, 2:15-19. MA S Q, WANG M, ZHOU J F, et al.Porcine epidemic diarrhea virus adapted to Vero cell culture and preparation of aluminum hydroxide inactivated vaccine by passing cytotoxicity[J].Infectious Diseases of Livestock and Poultry in China, 1994, 2:15-19.(in Chinese) [14] LIU Q, WANG H Y.Porcine enteric coronaviruses:An updated overview of the pathogenesis, prevalence, and diagnosis[J].Veterinary Research Communications, 2021, 45(2-3):75-86. [15] OPRIESSNIG T, GERBER P F, SHEN H, et al.Evaluation of the efficacy of a commercial inactivated genogroup 2b-based Porcine epidemic diarrhea virus (PEDV) vaccine and experimental live genogroup 1b exposure against 2b challenge[J].Veterinary Research, 2017, 48(1):69. [16] BAEK P S, CHOI H W, LEE S, et al.Efficacy of an inactivated genotype 2b Porcine epidemic diarrhea virus vaccine in neonatal piglets[J].Veterinary Immunology and Immunopathology, 2016, 174:45-49. [17] LIU X, ZHANG Q, ZHANG L, et al.A newly isolated Chinese virulent genotype GⅡb Porcine epidemic diarrhea virus strain:Biological characteristics, pathogenicity and immune protective effects as an inactivated vaccine candidate[J].Virus Research, 2019, 259:18-27. [18] XU X, DU L, FAN B, et al.A flagellin-adjuvanted inactivated Porcine epidemic diarrhea virus (PEDV) vaccine provides enhanced immune protection against PEDV challenge in piglets[J].Archives of Virology, 2020, 165(6):1299-1309. [19] 王诚诚.CTB蛋白联合PEDV灭活疫苗的小鼠免疫效果评估[D].广州:华南农业大学, 2018. WANG C C.Assessment of immune effect of PEDV inactivated vaccine combined with CTB protein in mice[D].Guangzhou:South China Agricultural University, 2018.(in Chinese) [20] 周川杰.CVC1302/CVC1303对PEDV灭活疫苗免疫增强机制初探[D].南京:南京农业大学, 2017. ZHOU C J.The immunological mechanism of CVC1302/CVC1303 to inactivated vaccine of Porcine epidemic diarrhea virus[D].Nanjing:Nanjing Agricultural University, 2017.(in Chinese) [21] HSUEH F C, CHANG Y C, KAO C F, et al.Intramuscular immunization with chemokine-adjuvanted inactive Porcine epidemic diarrhea virus induces substantial protection in pigs[J].Vaccines (Basel), 2020, 8(1):102. [22] JIN H, WU Y, BI S, et al.Higher immune response induced by vaccination in Houhai acupoint relates to the lymphatic drainage of the injection site[J].Research in Veterinary Science, 2020, 130:230-236. [23] 陈冰清, 葛艳, 司伏生, 等.猪流行性腹泻病毒诱导的猪肠道-乳腺-sIgA轴以及免疫机制探讨[J].微生物学通报, 2021, 48(11):4240-4249. CHEN B Q, GE Y, SI F S, et al.Gut-mammary-sIgA axis and immunologic mechanisms induced by Porcine epidemic diarrhea virus[J].Microbiology China, 2021, 48(11):4240-4249.(in Chinese) [24] ZHANG E, WANG J, LI Y, et al.Comparison of oral and nasal immunization with inactivated Porcine epidemic diarrhea virus on intestinal immunity in piglets[J].Experimental and Therapeutic Medicine, 2020, 20(2):1596-1606. [25] 王贵华, 侯艳红, 赵亚荣, 等.TGEV、PEDV二联活疫苗及其制备方法[P].北京:CN104784686B, 2019-07-16. WANG G H, HOU Y H, ZHAO Y R, et al.TGEV and PEDV combined live vaccine and its preparation method[P].Beijing:CN104784686B, 2019-07-16.(in Chinese) [26] 张许科, 孙进忠, 白朝勇.猪传染性胃肠炎病毒、猪流行性腹泻病毒和猪轮状病毒的三联活疫苗[P].河南:CN102949718B, 2015-06-17. ZHANG X K, SUN J Z, BAI C Y.Live triple vaccine of Porcine transmissible gastroenteritis virus, Porcine epidemic diarrhea virus and Porcine rotavirus[P].Henan:CN102949718B, 2015-06-17.(in Chinese) [27] PARK S J, SONG D S, PARK B K.Molecular epidemiology and phylogenetic analysis of Porcine epidemic diarrhea virus (PEDV) field isolates in Korea[J].Archives of Virology, 2013, 158(7):1533-1541. [28] SATO T, OROKU K, OHSHIMA Y, et al.Efficacy of genogroup 1 based porcine epidemic diarrhea live vaccine against genogroup 2 field strain in Japan[J].Virology Journal, 2018, 15(1):28. [29] WON H, LEE D U, JANG G, et al.Generation and protective efficacy of a cold-adapted attenuated genotype 2b Porcine epidemic diarrhea virus[J].Journal of Veterinary Science, 2019, 20(4):e32. [30] HOU Y, MEULIA T, GAO X, et al.Deletion of both the tyrosine-based endocytosis signal and the endoplasmic reticulum retrieval signal in the cytoplasmic tail of spike protein attenuates Porcine epidemic diarrhea virus in pigs[J]. Journal of Virology, 2019, 93(2):e01758-18. [31] LU Y, CAI H, LU M, et al.Porcine epidemic diarrhea virus deficient in RNA cap guanine-N-7 methylation is attenuated and induces higher type Ⅰ and Ⅲ interferon responses[J].Journal of Virology, 2020, 94(16):e00447-20. [32] HOU Y, KE H, KIM J, et al.Engineering a live attenuated Porcine epidemic diarrhea virus vaccine vandidate via inactivation of the viral 2'-O-methyltransferase and the endocytosis signal of the spike protein[J].Journal of Virology, 2019, 93(15):e00406-19. [33] CHANG Y C, CHANG C Y, TSAI P S, et al.Efficacy of heat-labile enterotoxin B subunit-adjuvanted parenteral Porcine epidemic diarrhea virus trimeric spike subunit vaccine in piglets[J].Applied Microbiology and Biotechnology, 2018, 102(17):7499-7507. [34] 郭涛.猪流行性腹泻病毒COE亚单位疫苗制备及免疫原性分析[D].石河子:石河子大学, 2021. GUO T.Preparation and immunogenicity analysis of Porcine epidemic diarrhea virus COE subunit vaccine[D].Shihezi:Shihezi University, 2021.(in Chinese) [35] MAKADIYA N, BROWNLIE R, VAN DEN HURK J, et al.S1 domain of the Porcine epidemic diarrhea virus spike protein as a vaccine antigen[J].Virology Journal, 2016, 13:57. [36] SUBRAMANIAM S, YUGO D M, HEFFRON C L, et al.Vaccination of sows with a dendritic cell-targeted Porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross pathological lesions in suckling neonatal piglets[J].The Journal of General Virology, 2018, 99(2):230-239. [37] YU J, SREENIVASAN C, UPRETY T, et al.Piglet immunization with a spike subunit vaccine enhances disease by Porcine epidemic diarrhea virus[J].NPJ Vaccines, 2021, 6(1):22. [38] HSU C W, CHANG M H, CHANG H W, et al.Parenterally administered Porcine epidemic diarrhea virus-like particle-based vaccine formulated with CCL25/28 chemokines induces systemic and mucosal immune protectivity in pigs[J].Viruses, 2020, 12(10):1122. [39] SEEGERS J F.Lactobacilli as live vaccine delivery vectors:Progress and prospects[J].Trends in Biotechnology, 2002, 20(12):508-515. [40] MA S, WANG L, HUANG X, et al.Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of Porcine epidemic diarrhea virus[J].Microbial Cell Factories, 2018, 17(1):20. [41] LI F, WANG X, FAN X, et al.Immunogenicity of recombinant-deficient Lactobacillus casei with complementary plasmid expressing alanine racemase gene and core neutralizing epitope antigen against Porcine epidemic diarrhea virus[J].Vaccines (Basel), 2021, 9(10):1084. [42] XIAO Y, WANG X, LI Y, et al.Evaluation of the immunogenicity in mice orally immunized with recombinant Lactobacillus casei expressing Porcine epidemic diarrhea virus S1 protein[J].Viruses, 2022, 14(5):890. [43] GUO T, GAO C, HAO J, et al.Strategy of developing oral vaccine candidates against co-infection of Porcine diarrhea viruses based on a Lactobacillus delivery system[J].Frontiers in Microbiology, 2022, 13:872550. [44] WANG J, HUANG L, MOU C, et al.Mucosal immune responses induced by oral administration recombinant Bacillus subtilis expressing the COE antigen of PEDV in newborn piglets[J].Bioscience Reports, 2019, 39(3):BSR20182028. [45] DO V T, JANG J, PARK J, et al.Recombinant adenovirus carrying a core neutralizing epitope of Porcine epidemic diarrhea virus and heat-labile enterotoxin B of Escherichia coli as a mucosal vaccine[J].Archives of Virology, 2020, 165(3):609-618. [46] JOSHI L R, OKDA F A, SINGREY A, et al.Passive immunity to Porcine epidemic diarrhea virus following immunization of pregnant gilts with a recombinant Orf virus vector expressing the spike protein[J].Archives of Virology, 2018, 163(9):2327-2335. [47] KE Y, YU D, ZHANG F, et al.Recombinant Vesicular stomatitis virus expressing the spike protein of genotype 2b Porcine epidemic diarrhea virus:A platform for vaccine development against emerging epidemic isolates[J].Virology, 2019, 533:77-85. [48] HAIN K S, JOSHI L R, OKDA F, et al.Immunogenicity of a recombinant Parapoxvirus expressing the spike protein of Porcine epidemic diarrhea virus[J].The Journal of General Virology, 2016, 97(10):2719-2731. [49] YIN Y, ZHU L, LIU P, et al.Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing S gene from Porcine epidemic diarrhea virus and VP7 gene from Porcine rotavirus[J].Brazilian Journal of Microbiology, 2019, 50(1):279-286. [50] GERDTS V, ZAKHARTCHOUK A.Vaccines for Porcine epidemic diarrhea virus and other swine Coronaviruses[J].Veterinary Microbiology, 2017, 206:45-51. [51] SAWATTRAKOOL K, STOTT C J, BANDALARIA-MARCA R D, et al.Field trials evaluating the efficacy of porcine epidemic diarrhea vaccine, RNA (Harrisvaccine) in the Philippines[J].Tropical Animal Health and Production, 2020, 52(5):2743-2747. [52] HO T T, NGUYEN G T, PHAM N B, et al.Plant-derived trimeric CO-26K-equivalent epitope induced neutralizing antibodies against Porcine epidemic diarrhea virus[J]. Frontiers in Immunology, 2020, 11:2152. [53] TIEN N Q, YANG M S, JANG Y S, et al.Systemic and oral immunogenicity of Porcine epidemic diarrhea virus antigen fused to poly-Fc of immunoglobulin G and expressed in ΔXT/FT Nicotiana benthamiana plants[J].Frontiers in Pharmacology, 2021, 12:653064. [54] HUY N X, TIEN N Q, KIM M Y, et al.Immunogenicity of an S1D epitope from Porcine epidemic diarrhea virus and cholera toxin B subunit fusion protein transiently expressed in infiltrated Nicotiana benthamiana leaves[J]. Plant Cell, Tissue and Organ Culture, 2016, 127(2):369-380. [55] DHAKAL S, RENUKARADHYA G J.Nanoparticle-based vaccine development and evaluation against viral infections in pigs[J]. Veterinary Research, 2019, 50(1):90. [56] 肖慎华, 阿得力江·吾斯曼, 刘振广.PLGA纳米疫苗佐剂的研究进展[J].江苏农业学报, 2022, 38(6):1715-1721. XIAO S H, WUSIMAN A, LIU Z G.Research progress of PLGA nano vaccine adjuvant[J].Jiangsu Journal of Agricultural Sciences, 2022, 38(6):1715-1721.(in Chinese) [57] LI B, DU L, YU Z, et al.Poly (D, L-lactide-co-glycolide) nanoparticle-entrapped vaccine induces a protective immune response against Porcine epidemic diarrhea virus infection in piglets[J].Vaccine, 2017, 35(50):7010-7017. [58] SU F, XU L, XUE Y, et al.Immune enhancement of nanoparticle-encapsulated ginseng stem-Leaf saponins on Porcine epidemic diarrhea virus vaccine in mice[J].Vaccines (Basel), 2022, 10(11):1810. [59] SHI D, FAN B, SUN B, et al.LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for Porcine epidemic diarrhea virus[J].Virology, 2022, 565:58-64. [60] 张玉琴, 孙业平, 齐建勋.抗病毒纳米颗粒疫苗的研究进展[J].药学进展, 2022, 46(10):751-760. ZHANG Y Q, SUN Y P, QI J X.Research progress of antiviral nanoparticle vaccines[J].Progress in Pharmaceutical Sciences, 2022, 46(10):751-760.(in Chinese) |
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