China Animal Husbandry and Veterinary Medicine ›› 2020, Vol. 47 ›› Issue (11): 3739-3748.doi: 10.16431/j.cnki.1671-7236.2020.11.038

• Preventive Veterinary Medicine • Previous Articles     Next Articles

Research Progress on Resistance of Salmonella Kentucky to Fluoroquinolones and Carbapenems

ZHANG Jingju, LIU Jing, XU Fei   

  1. National Feed Drug Benchmark Laboratory, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
  • Received:2020-06-08 Online:2020-11-20 Published:2020-11-20

Abstract: Salmonella Kentucky is another Salmonella serotype associated with human intestinal diseases following Salmonella Typhimurium and Salmonella Enteritidis.It is gradually attracting attention because of its strong ability to acquire and spread drug resistance.Among the many subserotypes of this serotype divided according to the sequence of multiple loci,ST198 subserotype has the characteristics of genomic islands that are easy to obtain drug resistance mutations,and has been evolving since the 21st century.In addition,resistance to fluoroquinolones and carbapenems have been acquired and spread worldwide,causing clinically difficult cases and the concern of the World Health Organization.This article summarizes the evolution of Salmonella Kentucky and highlights the resistance status and mechanism of Salmonella Kentucky with regard to fluoroquinolones and carbapenems,so as to provide a theoretical basis for the laboratory control and monitoring system of Salmonella in China.

Key words: Salmonella Kentucky; carbapenemase; drug resistance determination zone

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