›› 2018, Vol. 45 ›› Issue (11): 3296-3304.doi: 10.16431/j.cnki.1671-7236.2018.11.038

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Research Progress on Detection Methods of Avermectin Residues in Animal Origin Samples

LI Yuli, CHEN Kexin, TANG Taya, WU Yinghao, SHEN Jianzhong, CHENG Linli   

  1. College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
  • Received:2018-01-11 Online:2018-11-20 Published:2018-11-20

Abstract:

Currently,parasitic disease is one of the more serious zoonoses,and avermectins are the main drugs to control them in animal husbandry.Avermectins are macrolide antibiotics and all have powerful insect-resistant efficacy.However,they also have neurotoxicity and developmental toxins,and are highly fat-soluble.They are widely distributed in animals and have a long metabolic cycle.They are highly prone to cause drug residues in animal-derived foods and endanger human health through the food chain.It is important to detect the residue of avermectins in animal original samples.At present,the methods for analyzing avermectin residues in animal source samples include liquid chromatography-ultraviolet detection,liquid chromatography-fluorescence detection,enzyme-linked immunosorbent assay,liquid chromatography-tandem mass spectrometry,and so on.Here,the authors reviewed various methods for the detection of avermectins in animal original samples published in recent years,aiming at exploring the advantages and disadvantages of these methods and providing a reasonable basis for the more accurate and effective detection of the residues of avermectins in animal source food.

Key words: animal original sample; avermectins; maximum residue limits; residue analysis

CLC Number: