›› 2018, Vol. 45 ›› Issue (10): 2960-2968.doi: 10.16431/j.cnki.1671-7236.2018.10.035

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Simultaneous Determination of 8 Triazine Pesticides in Milk and Dairy Products from Total Diet by Isotope Dilution-High Performance Liquid Chromatography-Linear Ion Trap Mass Spectrometry

LI Peng1,2, YANG Xin1,2, MIAO Hong1,2, LI Jingguang1,2, ZHAO Yunfeng1,2, WU Yongning1,2   

  1. 1. China National Center For Food Safety Risk Assessment, Beijing 100021, China;
    2. Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing 100021, China
  • Revised:2018-05-15 Online:2018-10-20 Published:2018-10-20

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Abstract:

A method of the determination for 8 triazine pesticides in milk and dairy products from total diet was developed by isotope dilution-high performance liquid chromatography-linear ion trap mass spectrometry (HPLC-LIT-MS).Milk and dairy products from total diet were collected from 144 locations in China.Samples were ultrasonically extracted with acetonitrile,and then passed through gel permeation chromatography (GPC) to clear-up.The LC separation was performed on a CAPCELL PAK CR 1:20 column using acetonitrile and 10 mmol/L formic acid/0.1% formic aqueous solution as mobile phase.The ionization of the analytes was performed by electrospray mode.Selective reaction monitoring (SRM) was used for the monitoring of MS2 transitions for each compound.The one-to-one internal standards were used for quantation.The average recoveries were in the range of 83.9% to 103.3%.The relative standard deviations were 2.5% to 9.1%.The limits of detection (LODs) were 0.003 to 0.300 μg/kg.In conclusion,the method was suitable for dietary exposure assessment of 8 triazine pesticides in milk and dairy products from total diet.

Key words: triazine pesticides; milk and dairy products from total diet; HPLC-LIT-MS; gel permeation chromatography

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