瘦素基因的研究进展

doi:10.16431/j.cnki.1671-7236.2018.09.023

Abstract

Abstract:

Leptin is a protein hormone secreted by white adipose tissue.In mammals,leptin is a 16-ku peptide hormone that plays an important role in the energy balance of neuroendocrine and peripheral regulation,which is an important signal factor for reacting body fat content and regulating body weight and feeding.In human diseases,the expression of leptin gene plays an important regulatory role in many diseases.In particular,the mutation of leptin gene may lead to diseases such as obesity,diabetes and breast cancer.In animal husbandry,the expression of leptin gene has an significant impact on the intake and growth traits of cattle,sheep and pigs.In order to deepen the understanding of leptin gene,the distribution,structure and function of leptin are summarized,and the research advances on disease and animal husbandry in recent years are reviewed in this paper.

Key words: LEP gene; energy balance; signal factor

CLC Number:

Q756

LUO Zheng, WENG Jimei, FENG Junqi, XU Wei, LUO Weixing, CAI Huifen, CHEN Yue. Research Advances on Leptin Gene[J]. , 2018, 45(9): 2524-2530.

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