›› 2016, Vol. 43 ›› Issue (1): 63-67.doi: 10.16431/j.cnki.1671-7236.2016.01.010

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Advance on Prediction Methods of B-cell Antigen Epitope

MA Fan-shu, ZHANG Lei, WANG Yang, SUN Yan-gang, YAN Xi-jun   

  1. Institute of Special Wild Economic Animal and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, China
  • Received:2015-06-17 Online:2016-01-20 Published:2016-01-23

Abstract: Antigen epitopes are the basic functional units of antigen.B-cell antigen epitope prediction is important for vaccine design, development of diagnostic reagents and preparation of high-throughput antibody.This paper summarized the recent advances on prediction methods of B-cell linear epitopes and B-cell conformational epitopes, and compared these prediction methods in order to provide theoretical references for the researches of antigen epitopes.

Key words: B-cell antigen epitope; linear epitope; conformational epitope; epitope prediction

CLC Number: