牛IGF-1基因及其单核苷酸多态性与产奶性状关系的研究进展

摘要/Abstract

摘要： 产奶性状是奶牛生产中的重要经济性状，由微效多基因决定。影响奶牛产奶性状的基因较多，胰岛素样生长因子-1（insulin-like growth factor-1，IGF-1）基因作为影响奶牛产奶性状的一个候选基因，它的突变可导致其结构和功能发生改变，以及由此引起的产奶性状发生变化。作者就IGF-1的结构与功能及其基因单核苷酸多态性（single nucleotide polymorphisms，SNPs）与产奶性状的相关研究进展进行了综述，旨在为进行奶牛产奶性状的相关研究提供理论参考。

关键词:

牛; IGFmso-bidi-font-family: 宋体" lang="EN-US">-1基因; SNPs; 产奶性状; 研究进展

Abstract: Milk production traits were the important economic traits in the cow production，and were determined by many genes with little effect.Insulin-like growth factor-1 （IGF-1） gene as one of many candidate genes for milk production traits，the mutation of IGF-1 gene might result in the change of IGF-1 structure，and the change in milk production traits.The author reviewed the structure and function of IGF-1 gene and research progress on its single nucleotide polymorphisms and association with milk production traits in bovine，aiming to provide a theoretical reference for relevant studies on milk production traits.

Key words: font-size: 10.5pt; mso-bidi-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA" lang="EN-US">bovinefont-size: 10.5pt; mso-bidi-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">；IGFfont-size: 10.5pt; mso-bidi-font-family: 宋体; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA" lang="EN-US">-font-size: 10.5pt; mso-bidi-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA" lang="EN-US">1 genefont-size: 10.5pt; mso-bidi-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">；SNPs；milk production traits；research progress

霍秋红，杨芳，唐一波，江明生. 牛IGF-1基因及其单核苷酸多态性与产奶性状关系的研究进展[J]. 中国畜牧兽医.

HUO Qiu-hong，YANG Fang，TANG Yi-bo，JIANG Ming-sheng. Research Progress on Bovine IGF-1 Gene and Association of its SNPs with Milk Production Traits[J]. China Animal Husbandry & Veterinary Medicine.

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