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Epidemiological Investigation of Swine Hepatitis E

ZHANG Liang-quan, LIANG Huan-bin, WANG Heng, GAO Li-ze, WANG De-gang, YOU Jia, ZHANG Gui-hong   

  1. Key Laboratory of Animal Disease Control and Prevention of Ministry of Agriculture, Key Laboratory of Zoonoses Control and Prevention of Guangdong, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
  • Received:2012-02-23 Online:2012-08-20 Published:2012-08-24

Abstract: The present study was conducted to investigate the infection situation and prevailing characteristics of hepatitis E (HE) infection in swine herds in Guangdong. Antibodies of hepatitis E virus from 484 sera samples collected from Guangdong 2009 to 2011 were detected by double-antigen sandwich ELISA.Furthermore, strains of hepatitis E virus were isolated from 69 swine bile samples, in order to understand the genetic characteristics and evolution regularity of the virus. The results showed that the swine herds in Guangdong with a high antibody positive rate (71.9%) to HEV. Molecular epidemiology investigation showed that the epidemic strains in Guangdong was genotype Ⅳwith 71.0%(49/69)positive rate.

Key words: swine hepatitis E virus; double-antigen sandwich ELISA; epidemiology

CLC Number: