›› 2019, Vol. 46 ›› Issue (8): 2281-2287.doi: 10.16431/j.cnki.1671-7236.2019.08.011

• Physiology and Biochemistry • Previous Articles     Next Articles

Research Advances on Effects of Hypothalamic-pituitary-adrenal Axis in Animal Feeding Regulation

WU Hanyu, WANG Lina   

  1. Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China
  • Revised:2019-03-15 Online:2019-08-20 Published:2019-08-17

Abstract:

Feeding is the basic physiological process of animal survival, growth and development.Food intake of livestock and poultry directly affects the absorption of nutrients and production performance.In animal production, feeding is affected by many factors, and stress is one of the most important factors.The stress response of animal is mainly regulated by the hypothalamic-pituitary-adrenal (HPA) axis.The hypothalamus, pituitary and adrenal cortex regulate the stress response of the animals by releasing three stress hormones such as corticotropin releasing hormone (CRH), adrenocorticotropic hormone (ACTH) and glucocorticoid (GC).The regulation of feeding by stress hormones is a very complex process where it can regulates feed intake in both positive and negative way.Specifically, stress hormones may participate in both homeostatic and non-homeostatic pathways to regulate eating behavior.Homeostatic pathways refer to the regulation of food intake by sensing energy status of the body.In this case, CRH and ACTH inhibit feed intake by inhibiting the expression of the appetite peptide in the hypothalamus;GC plays a completely opposite role in the central and peripheral regions.The non-homeostatic pathways refer to the regulation of hedonic eating by modulating the midbrain reward system.It is a hotspot in the study of appetite regulation in recent years.More and more studies have focused on the crosstalk between stress hormone and reward system.In this review, the latest researches on regulation of feeding by stress hormone will be summarized.It will provide some theoretic basis for the development of new techniques on feeding regulation in animal production.

Key words: hypothalamus-pituitary-adrenal axis; stress; feeding

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