蛋白质组学及蛋白质翻译后修饰在畜牧领域中的应用研究进展

doi:10.16431/j.cnki.1671-7236.2019.04.013

摘要/Abstract

摘要：

蛋白质组学是一门全方位研究生命结构功能、生理功能及生命活动规律的新兴学科，已成为后基因组时代研究的重要内容，在很多领域得到广泛关注，同时为畜牧科学的发展与创新提供了全新的研究思路和技术手段。目前，蛋白质组学在畜禽生长发育、繁殖、营养、疾病、肉质等方面均有涉及，并通过各种研究手段发掘出一批与畜禽重要经济性状相关的蛋白质，对生产有重要的理论指导意义。蛋白质翻译后修饰（post-translation modifications，PTMs）作为蛋白质组学研究的一个重要分支，在增加蛋白质多样性和进行复杂生理学调控过程中发挥着重要的作用，能更好地揭示生命现象的本质与规律。作者对蛋白质组学及PTMs在畜牧领域中的应用研究进展进行了综述。

关键词: 蛋白质组学; 畜牧; 蛋白质翻译后修饰(PTMs)

Abstract:

Proteomics is a new subject that studies the function of life structure,physiology and life activities rule comprehensively,it has become an important part of post-genomics research,which has been extensively concerned in many fields,it also provides brand new research ideas and technical means for the development and innovation of animal science.At present,proteomics is involved in animal growth,reproduction,nutrition,disease and meat quality in livestock and poultry,and a batch of proteins related to the important economic traits have been mined through various methods,which contributes important theoretical reference for production.Post-translation modifications (PTMs) is an important branch of proteomics research,which plays an important role in increasing protein diversity and studying complex physiological regulatory process.The author reviews the advances and applications of proteomics and PTMs in animal husbandry.

Key words: proteomics; animal husbandry; protein post-translation modification (PTMs)

中图分类号:

Q816

王欣悦, 张莉. 蛋白质组学及蛋白质翻译后修饰在畜牧领域中的应用研究进展[J]. 《中国畜牧兽医》, 2019, 46(4): 1063-1073.

WANG Xinyue, ZHANG Li. Research Progress on Application of Proteomics and Post-translational Modification of Proteins in Animal Husbandry[J]. , 2019, 46(4): 1063-1073.

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