不同海拔地区牦牛血液生化指标的比较研究

doi:10.16431/j.cnki.1671-7236.2018.11.022

摘要/Abstract

摘要：

试验从心肌酶活性、肝脏代谢、肾脏代谢、机体抗氧化能力、能量代谢及脂代谢方面比较两个不同海拔地区的牦牛血液生化指标的差异，为牦牛高原低氧适应性提供理论依据。在青海省大通种牛场（较高海拔地区）采集牦牛血样49份，在河北省红松洼牧场（较低海拔地区）采集牦牛血样29份，检测25项血液生化指标，采用独立样本t检验对2个牦牛群体的检测结果进行比较分析。结果显示，与较低海拔地区牦牛相比，较高海拔地区牦牛血液生化指标中谷丙转氨酶（ALT）、谷草转氨酶（AST）、磷酸肌酸激酶同工酶（CK-MB）、α-羟丁酸脱氢酶（α-HBDH）、乳酸脱氢酶（LDH）活性及总胆红素（TBiL）、直接胆红素（DBiL）、总蛋白（TP）、球蛋白（GLB）、肌酐（CRE）、尿酸（UA）、丙二醛（MDA）、葡萄糖（GLU）水平极显著升高（P<0.01），碱性磷酸酶（ALP）活性显著升高（P<0.05）；超氧化物歧化酶（SOD）活性、血管内皮舒张因子（NO）、白蛋白（ALB）、甘油三酯（TG）水平及白球比（A/G）极显著降低（P<0.01）；其余指标均无显著差异（P>0.05）。结果表明，两个不同海拔地区的牦牛心肌酶活性、机体代谢功能及抗氧化能力存在一定差异，较高海拔地区的牦牛长期身处低氧环境，逐渐产生高原适应性。

关键词: 牦牛; 心肌酶活性; 肝脏代谢; 肾脏代谢; 抗氧化能力; 高原低氧适应

Abstract:

This study was designed to compare the myocardial enzymes activity,liver metabolism,kidney metabolism and some other biochemical indicators related to body antioxidant capacity,energy metabolism and lipid metabolism between yaks at two different altitudes.49 blood samples of yaks were collected in Datong,Qinghai (higher altitude) and 29 blood samples of yaks were collected in Hongsongwa farm,Hebei (lower altitude).25 blood biochemical indicators were tested and the results of the two groups were compared with independent t-tests.The results showed that,compared with yaks at lower altitude,the activities of blood ALT,AST,CK-MB,α-HBDH and LDH,the levels of blood TBiL,DBiL,TP,GLB,CRE,UA,MDA,and GLU in yaks at higher altitude were extremely significantly higher (P<0.01),and the activity of ALP were significantly higher (P<0.05) as well.While the SOD activity,NO,ALB and TG levels,and A/G were extremely significantly decreased (P<0.01).The rest of the indicators showed no significant difference (P>0.05).In conclusion,there were certain differences in myocardial enzyme activity,metabolic function and antioxidant capacity of yaks at two different altitudes,and yaks at higher altitude had been on the plateau for a long time and gradually developed the adaptability to the plateau hypoxia environment.

Key words: yak; myocardial enzymes activity; liver metabolism; kidney metabolism; antioxidant capacity; altitude acclimatization

中图分类号:

S823.8⁺5

雷蕾, 包鹏甲, 吴晓云, 褚敏, 梁春年, 阎萍. 不同海拔地区牦牛血液生化指标的比较研究[J]. 《中国畜牧兽医》, 2018, 45(11): 3160-3166.

LEI Lei, BAO Pengjia, WU Xiaoyun, CHU Min, LIANG Chunnian, YAN Ping. Comparison Study of Blood Biochemical Indicators of Yak at Different Altitudes[J]. , 2018, 45(11): 3160-3166.

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