葡萄糖氧化酶对仔猪生长性能和血清生化指标的影响

doi:10.16431/j.cnki.1671-7236.2018.08.021

摘要/Abstract

摘要：

试验研究了日粮中添加葡萄糖氧化酶（GOD）对仔猪生长性能、血清生化指标的影响。选用28日龄健康断奶仔猪60头，公母各半，随机分为3组：对照组（基础日粮）、试验1组（基础日粮中添加抗生素（喹乙醇100 g/t，金霉素75 g/t，土霉素钙60 g/t））及试验2组（基础日粮中添加400 g/T的GOD），每组4个重复，每个重复5头猪。试验期31 d，测定试验期间仔猪的生长性能及试验结束时仔猪血清生化指标。结果表明：日粮中添加GOD后，仔猪末重、平均日增重（ADG）均显著高于对照组和试验1组（P<0.05），日均采食量（ADFI）和料重比（F/G）均显著低于对照组和试验1组（P<0.05）；血清谷草转氨酶（AST）活性显著低于对照组和试验1组（P<0.05），血清谷丙转氨酶（ALT）活性、总蛋白（TP）、白蛋白（ALB）和球蛋白（GLB）水平未有显著变化（P>0.05）；血清丙二醛（MDA）含量显著低于对照组（P<0.05），血清谷胱甘肽过氧化物酶（GSH-Px）、总超氧化物歧化酶活性（SOD）和总抗氧化能力（T-AOC）均有提高，但差异不显著（P>0.05）；血清免疫球蛋白A、G、M（IgA、IgG、IgM）和肿瘤坏死因子-α（TNF-α）均显著高于对照组和试验1组（P<0.05），干扰素-γ（IFN-γ）显著高于对照组（P<0.05），白细胞介素2（IL-2）和白细胞介素4（IL-4）水平均高于对照组和试验1组，但差异不显著（P>0.05）。综合以上试验结果，在日粮中添加400 g/t的GOD可有效改善仔猪血液抗氧化能力，提高仔猪生长性能，缓解仔猪的肝脏损伤。

关键词: 葡萄糖氧化酶(GOD); 抗生素; 仔猪; 生长性能; 血清生化指标

Abstract:

This study was conducted to elucidate the effects of glucose oxidase (GOD) on growth performance and serum biochemical indicator of piglets.Sixty piglets were randomized in three groups,control group (basal diet),experimental group 1(basal diet added 100 g/t olaquindox,75 g/t aureomycin,60 g/t oxytetracycline calcium) and experimental group 2 (basal diet added 400 g/t GOD).Each group had four replicates and each replicate had five piglets.The experiment lasted 30 d.The growth performance during the experiment and the serum biochemical indexes at the ending of the experiment were measured.The results showed that:For the pigs in experimental group 2,the final body weight,ADG,the level of IL-2,IL-4,IgA,lgG,IgM and TNF-α were all significantly higher (P<0.05),while the ADFI,F/G and surem AST activity were significantly lower (P<0.05) than that in control group and experimeatal group 1;The serum level of MDA was significantly lower than that in control group (P<0.05),while the IFN-γ level was significantly higher than control group (P<0.05);The other serum biochemical indexes,such as the activities of ALT,GSH-Px and SOD,the level of TP,ALB and GLB,and T-AOC had no significantly change(P>0.05).In conclusion,adding 400 g/t GOD in diets could improve the growth performance and antioxidant and immune ability,alleviate liver damage of piglets.

Key words: glucose oxidase (GOD); antibiotics; piglets; growth performance; serum biochemical indexes

中图分类号:

S816.7

穆淑琴, 李宁, 闫峻, 郑梓, 马墉, 李千军, 张春华. 葡萄糖氧化酶对仔猪生长性能和血清生化指标的影响[J]. 《中国畜牧兽医》, 2018, 45(8): 2212-2218.

MU Shuqin, LI Ning, YAN Jun, ZHENG Zi, MA Yong, LI Qianjun, ZHANG Chunhua. Effect of Glucose Oxidase on Growth Performance and Serum Biochemical Indexes of Piglets[J]. , 2018, 45(8): 2212-2218.

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