《中国畜牧兽医》 ›› 2017, Vol. 44 ›› Issue (6): 1869-1876.doi: 10.16431/j.cnki.1671-7236.2017.06.041

• 基础兽医 • 上一篇    下一篇

几种兽用合成抗菌药基于抗体快速检测技术研究进展

韩肖亚, 陈冬梅, 王玉莲, 陶燕飞, 董国良, 彭大鹏, 袁宗辉   

  1. 华中农业大学, 国家兽药残留基准实验室(HZAU), 农业部兽药残留检测重点实验室, 武汉 430070
  • 收稿日期:2016-09-30 出版日期:2017-06-20 发布日期:2017-06-28
  • 通讯作者: 彭大鹏,袁宗辉 E-mail:pengdapeng@mail.hzau.edu.cn;yuan5802@mail.hzau.edu.cn
  • 作者简介:韩肖亚(1990-),女,河南开封人,硕士生,研究方向:兽药残留与食品安全,E-mail:hxy160901@163.com
  • 基金资助:

    青年教师科技创新专项(2662017PY049)

Research Progress on Antibodies Rapid Detection Technology for Veterinary Synthetic Antibacterial Agents

HAN Xiao-ya, CHEN Dong-mei, WANG Yu-lian, TAO Yan-fei, DONG Guo-liang, PENG DA-peng, YUAN Zong-hui   

  1. MOA Key Laboratory for Detection of Veterinary Drug Residues, National Reference Laboratory of Veterinary Drug Residues (HZAU), Huazhong Agricultural University, Wuhan 430070, China
  • Received:2016-09-30 Online:2017-06-20 Published:2017-06-28

摘要:

合成抗菌药在预防、治疗动物疾病等方面应用十分广泛,但不合理使用造成的耐药及残留问题日益严重,因此对兽用合成抗菌药的残留检测势在必行,而基于抗体的快速检测技术具有简便、灵敏度高、成本低等优点,发展前景十分广阔。作者综述了近年来针对磺胺类、氟喹诺酮类、喹噁啉类、硝基呋喃类、硝基咪唑类5大类兽用合成抗菌药物的抗体检测技术最新研究趋势,旨在促进残留快速检测技术的发展。

关键词: 合成抗菌药; 兽药残留; 抗体; 快速检测技术

Abstract:

Synthetic antibacterial agents are widely used in prevention and treatment of animal diseases. However, the irrational drugs use has caused severe drug residues issues and bacteria resistance.Therefore,it is particularly important to develop the rapid detection technology.The antibodies rapid detection technology has broad prospects because of its high sensitivity, simplicity, and low cost. The author reviewed the latest research on antibodies preparation and rapid detection methods for sulfonamides,fluoroquinolones, quinoxalines, nitrofurans and nitroimidazoles. It is great significant for the development of antibody rapid detection methods on the veterinary drug residues.

Key words: synthetic antibacterial agents; veterinary drug residues; antibody; rapid detection methods

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