《中国畜牧兽医》---唯一指定的官方网站 ›› 2015, Vol. 42 ›› Issue (3): 708-713.doi: 10.11843/j.issn.1671-7236.2015.03.031

• 疾病防治 • 上一篇    下一篇

"香连"溶液干膏剂体外抑菌试验研究

邱园园, 韩金潭, 孙翠翠, 王赛, 刘群   

  1. 西南民族大学生命科学与技术学院, 成都 610041
  • 收稿日期:2014-11-03 出版日期:2015-03-20 发布日期:2015-03-30
  • 通讯作者: 刘群 E-mail:liuqun2567@163.com
  • 作者简介:邱园园(1987-),女,河南信阳人,硕士生,研究方向:中药药理学,E-mail:471604192@qq.com
  • 基金资助:

    国家"十二五"科技支撑计划项目(2011BAD34B02-4);兽医专业学位研究生省级教育实践基地建设

Study on Bacteriostasis in Vitro of "Xianglian" Solution Dry Paste

QIU Yuan-yuan, HAN Jin-tan, SUN Cui-cui, WANG Sai, LIU Qun   

  1. College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China
  • Received:2014-11-03 Online:2015-03-20 Published:2015-03-30

摘要: 本试验旨在探讨中草药体外抑菌作用,为纯中草药消毒剂的临床使用和扩大临床使用范围提供科学依据.本试验以金黄色葡萄球菌、大肠杆菌、沙门氏菌为模式菌株,以抑菌圈直径、抑菌浓度、细菌生长曲线和抑菌温度曲线为检测指标,研究纯中草药消毒剂"香连"溶液干膏剂的抑菌活性.试验结果显示,对3种模式菌株的抑杀效果由强到弱依次为金黄色葡萄球菌、大肠杆菌、沙门氏菌,MIC分别为7.81、31.25、250 mg/mL,所需时间分别为2、2、6 h,对金黄色葡萄球菌、沙门氏菌抑杀环境温度为25、37℃.结果表明,"香连"溶液消毒剂不仅可作为环境消毒剂,也可作为饮水消毒剂和细菌性疾病的治疗药物.

关键词: 纯中草药消毒剂; 体外抑菌作用; 临床应用范围

Abstract: The study was aimed to investigate the effect of bacteriostasis in vitro of Chinese herbal medicine,and provide scientific basis for the clinical use of pure Chinese herbal disinfectant and expanding the scope of its clinical use.To study the antibacterial activity of pure Chinese herbal disinfectant "Xianglian" solution dry paste,Staphylococcus aureus,Escherichia coli and Salmonella strains were used as the type strains,the inhibition zone diameter,inhibitory concentration,growth curve of bacteria and bacteriostatic temperature curve were detected in this study.The results showed that the killing effect of 3 type strains from strong to weak were Staphylococcus aureus,Escherichia coli,Salmonella;The corresponding MIC were 7.81,31.25 and 250 mg/mL,respectively;The corresponding required time were 2,2 and 6 h,respectively;And the environment temperature of inhibiting and killing Staphylococcus aureus and Salmonella were 25 and 37℃,respectively.The research results showed that "Xianglian" solution not only could be used as environmental disinfectant,but also could be used as drinking water disinfectant and therapeutic drug in bacterial diseases.

Key words: pure Chinese herbal disinfectant; bacteriostasis in vitro; clinical application range

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