[1] MICHISHITA E,MCCORD R A,BERBER E,et al.SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin[J].Nature,2008,452(7186):492-496. [2] MICHISHITA E,MCCORD R A,BOXER L D,et al.Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6[J].Cell Cycle,2009,8(16):2664-2666. [3] MAO Z,HINE C,TIAN X,et al.SIRT6 promotes DNA repair under stress by activating PARP1[J].Science,2011,332(6036):1443-1446. [4] RIZZO A,IACHETTINI S,SALVATI E,et al.SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage[J].Nucleic Acids Research,2017,45(4):1820-1834. [5] CARDUS A,URYGA A K,WALTERS G,et al.SIRT6 protects human endothelial cells from DNA damage,telomere dysfunction,and senescence[J].Cardiovascular Research,2013,97(3):571-579. [6] KAIDI A,WEINERT B T,CHOUDHARY C,et al.Human SIRT6 promotes DNA end resection through CtIP deacetylation[J].Science,2010,329(5997):1348-1353. [7] VAN METER M,SIMON M,TOMBLINE G,et al.JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks[J].Cell Reports,2016,16(10):2641-2650. [8] MCCORD R A,MICHISHITA E,HONG T,et al.SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair[J].Aging,2009,1(1):109-121. [9] MOSTOSLAVSKY G,MOSTOSLAVSKY R,CHUA K F,et al.Genomic instability and aging-like phenotype in the absence of mammalian SIRT6[J].Cell,2006,124(2):315-329. [10] KANFI Y,NAIMAN S,AMIR G,et al.The sirtuin SIRT6 regulates lifespan in male mice[J].Nature,2012,483(7388):218-221. [11] ZHAI X,YAN P,ZHANG J,et al.Knockdown of SIRT6 enables human bone marrow mesenchymal stem cell senescence[J].Rejuvenation Research,2016,19(5):373-384. [12] MINAGAWA S,ARAYA J,NUMATA T,et al.Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-beta-induced senescence of human bronchial epithelial cells[J].American Journal of Physiology-Lung Cellular and Molecular Physiology,2011,300(3):L391-L401. [13] HU J Q,DENG F,HU X P,et al.Histone deacetylase SIRT6 regulates chemosensitivity in liver cancer cells via modulation of FOXO3 activity[J].Oncology Reports,2018,40(6):3635-3644. [14] BAE J S,NOH S J,KIM K M,et al.SIRT6 is involved in the progression of ovarian carcinomas via β-catenin-mediated epithelial to mesenchymal transition[J].Frontiers in Oncology,2018,8:538. [15] 沈自尹,陈洋,平键,等.淫羊藿苷提高SIRT6酶活性及抑制小鼠NF-κB炎症信号通路的实验研究[J].老年医学与保健,2012,18(6):338-346. SHEN Z Y,CHEN Y,PING J,et al.Experimental research of improvement of SIRT6 enzymatic activity and inhibition of NF-κB inflammatory signaling transduction in mice by Icarri[J].Geriatrics & Health Care,2012,8(6):338-346.(in Chinese) [16] ZHONG L,D'URSO A,TOIBER D,et al.The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α[J].Cell,2010,140(2):280-293. [17] KIM H,XIAO C,WANG R,et al.Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis[J].Cell Metabolism,2010,12(3):224-236. [18] GUI L,JIANG B,ZHANG Y,et al.Sequence variants in the bovine silent information regulator 6,their linkage and their associations with body measurements and carcass quality traits in Qinchuan cattle[J].Gene,2015,559(1):16-21. [19] GUI L,RAZA S H A,GARCIA M,et al.Genetic variants in the SIRT6 transcriptional regulatory region affect gene activity and carcass quality traits in indigenous Chinese beef cattle (Bos taurus)[J].BMC Genomics,2018,19(1):785. [20] HONG J,MEI C,LI S,et al.Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes[J].Archives of Biochemistry and Biophysics,2018,659:1-12. [21] MAHLKNECHT U,HO A D,VOELTER-MAHLKNECHT S.Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene[J].International Journal of Oncology,2006,28(2):447-456. [22] GERTLER A A,COHEN H Y.SIRT6,a protein with many faces[J].Biogerontology,2013,14(6):629-639. [23] NASSIM D,MARIE L,SÉBASTIEN F,et al.Sirtuins:The ‘magnificent seven’,function,metabolism and longevity[J].Annals of Medicine,2007,39(5):335-345. [24] LISZT G,FORD E,KURTEV M,et al.Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase[J].Journal of Biological Chemistry,2005,280(22):21313-21320. [25] DE FELICI M.Experimental approaches to the study of primordial germ cell lineage and proliferation[J].Human Reproduction Update,2004,10(3):197-206. |